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RAB0904

Rat Ins1 / Insulin ELISA Kit

Synonym(s):

Rat ELISA

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About This Item

NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
rat ... Ins1(24505)
Input:
sample type serum
sample type cell culture supernatant(s)
sample type plasma
Species reactivity:
rat
Storage temp.:
−20°C
Shipped in:
wet ice
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species reactivity

rat

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type serum
sample type cell culture supernatant(s)
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 5 μIU/mL
standard curve range: 4.69–300 μIU/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

rat ... Ins1(24505)

General description

The antibody pair provided in this kit recognizes Rat Insulin.

Application

Rat Ins1 / Insulin ELISA Kit has been used to measure serum insulin concentration.
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Certain organisms such as mice, rat and xenopus possess two non-allelic insulin genes. These genes are Ins1 and Ins2, which are both functional. They encode insulin that is produced in a 1:2 ratio, respectively in the pancreas. The two genes are differentially expressed in mouse. The Ins1 gene maps to mouse chromosome 19 in the telomeric region. The insulin that is synthesized in the pancreas is crucial in maintaining glucose homeostasis. Loss of Ins-1 and Ins-2 expression leads to insulin deficient mice with diabetes mellitus, ketoacidosis, liver steatosis and retarded growth.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Kit Components Also Available Separately

Product No.
Description
SDS

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS

  • RABSTOP3ELISA Stop Solution (Item I)SDS

  • RABWASH420X Wash Buffer (Item B)SDS

pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Storage Class

10 - Combustible liquids

Regulatory Information

低风险生物材料
常规特殊物品

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Jingjing Li et al.
Neural plasticity, 2019, 7920540-7920540 (2019-03-27)
We investigated the effects of aerobic exercise on the expression of hippocampal synaptic plasticity-associated proteins in rats with type 2 diabetes and their possible mechanisms. A type 2 diabetes rat model was established with 8 weeks of high-fat diet combined
Amanda C Okolie et al.
Bioscience reports, 39(2) (2017-08-10)
Recent studies have shown that Type 2 diabetes (T2D) in rats can result through a synergy that links obesity to insulin resistance and β-cell dysfunction. The present study achieved T2D via high fructose (20%w/v, p.o.), streptozotocin single dose (40 mg/kg
Hongtao Tan et al.
Molecular medicine (Cambridge, Mass.), 28(1), 58-58 (2022-05-21)
Glabridin (Glab) is a bioactive component of licorice that can ameliorate diabetes, but its role in diabetic nephropathy (DN) has seldom been reported. Herein, we explored the effect and underlying mechanism of Glab on DN. The bioactive component-target network of
Sadi Loai et al.
Frontiers in cardiovascular medicine, 9, 886687-886687 (2022-06-07)
To uncover sex-related microvascular abnormalities that underlie the early presentation of reduced perfusion in leg skeletal muscle in a type II rat model of diabetic cardiomyopathy. Diabetes was induced using a non-obese, diet-based, low-dose streptozotocin model in adult female (18
Sadi Loai et al.
Frontiers in cardiovascular medicine, 8, 715400-715400 (2021-08-07)
Aim: To perform a deep cardiac phenotyping of type II diabetes in a rat model, with the goal of gaining new insight into the temporality of microvascular dysfunction, cardiac dysfunction, and exercise intolerance at different stages of diabetes. Methods and

Global Trade Item Number

SKUGTIN
RAB0904-1KT04061835166664

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