RAB1127
Mouse PAI-1 ELISA Kit
for cell culture supernatants, plasma, and serum samples
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About This Item
NACRES:
NA.32
UNSPSC Code:
41116158
Species reactivity:
mouse, human
Storage temp.:
−20°C
Shipped in:
wet ice
species reactivity
mouse, human
technique(s)
ELISA: suitable
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 80 pg/ml
shipped in
wet ice
storage temp.
−20°C
General description
The PAI-1 (plasminogen activator inhibitor) gene is localized to human chromosome 7q22.1. Active form of PAI-1 is expressed in the blood and tissues. Platelets harbor both the active and latent forms of PAI-1.
This ELISA antibody pair detects mouse and human PAI-1.
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.
Please refer to the attached Protocolfor details.
Biochem/physiol Actions
PAI-1 (plasminogen activator inhibitor) produced by platelets takes part in stabilizing blood clotting mechanism. PAI-1 prevents plasminogen activation during fibrinolysis. This might lead to the risk of cardiovascular disease. Elevated levels of PAI-1 has been observed in type 2 diabetes mellitus and serves the reason for reduced insulin sensitivity. PAI-1 stimulates the process of cellular senescence. PAI-1 regulation occurs through p53 dependent TGF-β (transforming growth factor-β) signalling. Studies also also predict that stress and depression might influence PAI-1 expression.
Other Notes
A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.
Signal Word
Danger
Hazard Codes
Precautionary Statements
Hazard Classifications
Resp. Sens. 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
Storage Class
10 - Combustible liquids
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