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RDD021

Sigma-Aldrich

Sodium dodecyl sulfate

anhydrous, free-flowing, Redi-Dri™, ACS reagent, ≥99.0%

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Synonym(s):
Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate
Linear Formula:
CH3(CH2)11OSO3Na
CAS Number:
151-21-3
Molecular Weight:
288.38
Beilstein:
3599286
EC Number:
205-788-1
MDL number:
MFCD00036175
PubChem Substance ID:
329824230
NACRES:
NA.21

grade

ACS reagent
anhydrous

Quality Level

100

description

anionic

product line

Redi-Dri™

Assay

≥99.0%

quality

free-flowing

mol wt

288.38 g/mol

impurities

≤0.06 meq/g Titr. Base
≤4.0% unsulfated alcohols
≥96.0% fatty alcohols

loss

≤1.0% loss on drying

mp

204-207 °C (lit.)

solubility

water: soluble 100 mg/mL (opalescent solution)

cation traces

heavy metals (as Pb): ≤0.002%

λ

3 %H2O reference

UV absorption

λ: 230-350 nm Amax: ≤0.1

SMILES string

[Na+].CCCCCCCCCCCCOS([O-])(=O)=O

InChI

1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1

InChI key

DBMJMQXJHONAFJ-UHFFFAOYSA-M

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General description

SDS (sodium dodecyl sulfate) is a wetting agent and an anionic detergent which functions efficiently in both alkaline and acidic solutions. It is generally used for the solubilization of lipids and proteins. It also functions as a potent protein denaturant. SDS, volume-wise, is one of the most commonly used synthetic surfactants.

Application

Anionic detergent

Legal Information

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H302 - H315 - H318 - H412

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

338.0 °F

Flash Point(C)

170 °C

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Toxicity of anionic detergents determined by Saccharomyces cerevisiae microarray analysis.
Sirisattha S et al
Water Research, 38(1), 61-70 (2004)
Antony Anet et al.
Journal of hazardous materials, 370, 42-53 (2018-09-15)
This study investigates Bisphenol A (BPA) induced oxidative stress that mediates the genotoxicity in in vivo model Drosophila melanogaster. The calculated LC50 for BPA was 12.35 μg/mL. The strains of D. melanogaster were reared in 0.1, 1.0, 2.5 and 5.0 μg/mL BPA
M D Womack et al.
Biochimica et biophysica acta, 733(2), 210-215 (1983-09-07)
Over 50 detergents were tested to establish which would be most effective in releasing proteins from membrane-bounded compartments without denaturing them. Various concentrations each of detergent were tested for two activities: (1) solubilization of egg phospholipid liposomes as measured by
Erdem D Tabdanov et al.
Cell reports, 25(2), 328-338 (2018-10-12)
Cancer cell migration through and away from tumors is driven in part by migration along aligned extracellular matrix, a process known as contact guidance (CG). To concurrently study the influence of architectural and mechanical regulators of CG sensing, we developed
Daniel Zingg et al.
Cancer cell, 34(1), 69-84 (2018-07-17)
Human melanomas frequently harbor amplifications of EZH2. However, the contribution of EZH2 to melanoma formation has remained elusive. Taking advantage of murine melanoma models, we show that EZH2 drives tumorigenesis from benign BrafV600E- or NrasQ61K-expressing melanocytes by silencing of genes

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