RES3077T-A7
Tricine
Synonym(s):
Tricine, N-[Tris(hydroxymethyl)methyl]glycine
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About This Item
Linear Formula:
(HOCH2)3CNHCH2CO2H
CAS Number:
Molecular Weight:
179.17
EC Number:
227-193-6
UNSPSC Code:
12161700
NACRES:
NA.21
Beilstein/REAXYS Number:
1937804
MDL number:
eCl@ss:
32150319
biological source
synthetic
form
powder
technique(s)
cell culture | mammalian: suitable, pH adjustment: suitable
impurities
Endotoxin, microbial, and trace metals; tested
useful pH range
7.4-8.8
pKa (25 °C)
8.1
suitability
suitable for manufacturing use
application(s)
downstream processes
pharma/biopharma processes
foreign activity
Cytotoxicity, DNase, NICKase, RNase, and Protease; tested
SMILES string
OCC(CO)(CO)NCC(O)=O
InChI
1S/C6H13NO5/c8-2-6(3-9,4-10)7-1-5(11)12/h7-10H,1-4H2,(H,11,12)
InChI key
SEQKRHFRPICQDD-UHFFFAOYSA-N
General description
Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.
M-Clarity Program
Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.
Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.
M-Clarity Program
Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.
Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.
Application
Buffer component for separation of low molecular weight peptides.
Tricine is a biological buffer often referred to as a “Good′s” buffer. The pKa of Tricine is 8.1 which makes Tricine is a good candidate for biological applications that require pH control above physiological. Tricine is considered to be non-toxic to culture cell lines, highly water soluble and provides high-solution clarity.
Tricine can be used in a wide array of biological applications including as a component in media formulations. Specific applications include buffers for electrophoresis, protein purification and diagnostic reagent production.
Tricine can be used in a wide array of biological applications including as a component in media formulations. Specific applications include buffers for electrophoresis, protein purification and diagnostic reagent production.
Packaging
Product is available in the following package sizes:
RES3077T-A701X: 100 gm container
RES3077T-A702X: 1 kg container
RES3077T-A704X: 10 kg container
RES3077T-A705X: 25 kg container
RES3077T-A701X: 100 gm container
RES3077T-A702X: 1 kg container
RES3077T-A704X: 10 kg container
RES3077T-A705X: 25 kg container
Legal Information
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
13 - Non Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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