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S0814

Anti-phospho-Serotonin N-Acetyltransferase (N-Terminal) (pThr29) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
western blot
Species reactivity:
rat
Citations:
4
Technique(s):
western blot: 0.5 μg/mL
Uniprot accession no.:
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Product Name

Anti-phospho-Serotonin N-Acetyltransferase (N-Terminal) (pThr29) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution

storage temp.

−20°C

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

rat

technique(s)

western blot: 0.5 μg/mL

UniProt accession no.

shipped in

dry ice

target post-translational modification

phosphorylation (pThr29)

Quality Level

Gene Information

rat ... Aanat(25120)

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunocytochemistry (1 paper)

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

synthetic phosphopeptide derived from the N-terminal region of rat AA-NAT that contains threonine 29.

Physical form

Solution in phosphate buffered saline, containing 1 mg/ml BSA and 0.05% sodium azide.

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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Marco A Pires-Lapa et al.
International journal of molecular sciences, 19(8) (2018-07-28)
Melatonin (5-methoxy-N-acetylserotonin), the pineal hormone, is also synthesized by immune-competent cells. The pineal hormone signals darkness, while melatonin synthesized on demand by activated macrophages at any hour of the day acts locally, favoring regulatory/tolerant phenotypes. Activation of β-adrenoceptors in pinealocytes
Claudia Emanuele Carvalho-Sousa et al.
Journal of pineal research, 68(3), e12636-e12636 (2020-02-12)
Environmental pollution in the form of particulate matter <2.5 μm (PM2.5 ) is a major risk factor for diseases such as lung cancer, chronic respiratory infections, and major cardiovascular diseases. Our goal was to show that PM2.5 eliciting a proinflammatory response
Sandra Marcia Muxel et al.
PloS one, 7(12), e52010-e52010 (2013-01-04)
We demonstrate that during inflammatory responses the nuclear factor kappa B (NF-κB) induces the synthesis of melatonin by macrophages and that macrophage-synthesized melatonin modulates the function of these professional phagocytes in an autocrine manner. Expression of a DsRed2 fluorescent reporter
Marlina O Córdoba-Moreno et al.
Scientific reports, 10(1), 4799-4799 (2020-03-18)
Daily oscillation of the immune system follows the central biological clock outputs control such as melatonin produced by the pineal gland. Despite the literature showing that melatonin is also synthesized by macrophages and T lymphocytes, no information is available regarding

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