Key Documents

View All Documentation

S0885

Somatostatin

Name: Somatostatin
Brand: SIGMA

powder, γ-irradiated, BioXtra, suitable for cell culture

Synonym(s):

Growth hormone release inhibiting factor, SRIF, Somatostatin-14, Somatotropin release inhibiting factor

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₇₆H₁₀₄N₁₈O₁₉S₂

CAS Number:

38916-34-6

Molecular Weight:

1637.88

UNSPSC Code:

12352209

NACRES:

NA.77

PubChem Substance ID:

24899450

EC Number:

254-186-5

Beilstein/REAXYS Number:

6436064

MDL number:

MFCD00076762

Biological source:

synthetic (organic)

Form:

powder

Assay:

≥50%

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

biological source

synthetic (organic)

Quality Segment

200

sterility

γ-irradiated

product line

BioXtra

assay

≥50%

form

powder

potency

0.3-50 ng/mL

concentration

≥50% (HPLC)

technique(s)

cell culture | mammalian: suitable

solubility

cell culture medium: 10 mL/vial

shipped in

ambient

storage temp.

−20°C

SMILES string

[H]N1[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc4c[nH]c5ccccc45)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc6ccccc6)C(=O)N[C@@H]([C@@H](C)O)C(=O)NC(CO)C(=O)N[C@@H](CSSC[C@H](NC(=O)CNC(=O)[C@H](C)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C1=O)C(O)=O

InChI

1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)/t41-,42+,43+,50-,51-,52-,53-,54-,55-,56-,57?,58-,59-,62-,63-/m0/s1

InChI key

NHXLMOGPVYXJNR-FQSIDJEASA-N

Gene Information

human ... SSTR1(6751), SSTR2(6752), SSTR3(6753), SSTR4(6754), SSTR5(6755)

Description

Biochem/physiol Actions

Somatostatin regulates endocrine function and cell proliferation via interaction with G-protein-coupled somatostatin receptors. It exists in two active forms produced by alternative cleavage of a single preproprotein (14 aa and 28 aa forms). Somatosatin inhibits the release of growth hormone; thyroid-stimulating hormone and a range of gastrointestinal hormones: Cholecystokinin (CCK); Enteroglucagon; Gastrin; Gastric inhibitory polypeptide (GIP); Motilin; Secretin; Vasoactive intestinal peptide (VIP).

Physical form

powder-0 °C; stock-frozen in working aliquots, avoid repeated freeze/thaw

Preparation Note

To prepare 2 μg/ml stock solution, add 10 ml sterile culture medium.

Still not finding the right product?

Explore all of our products under Somatostatin

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c