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Merck
CN

S1172

Anti-Syntaxin 1 antibody produced in rabbit

IgG fraction of antiserum, lyophilized powder

Synonym(s):

Anti-GEFSP9, Anti-STX1B1, Anti-STX1B2

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
immunohistochemistry
western blot (chemiluminescent)
Species reactivity:
mouse, rat
Citations:
19
Technique(s):
immunohistochemistry: suitable using rat brain sections
western blot (chemiluminescent): 1:1,000 using rat brain membranes
Uniprot accession no.:
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Product Name

Anti-Syntaxin 1 antibody produced in rabbit, IgG fraction of antiserum, lyophilized powder

biological source

rabbit

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

mouse, rat

technique(s)

immunohistochemistry: suitable using rat brain sections
western blot (chemiluminescent): 1:1,000 using rat brain membranes

UniProt accession no.

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

Application

Anti-Syntaxin 1 antibody has been used in western blotting and immunohistochemistry.

Biochem/physiol Actions

Syntaxin 1 (STX1A) may control exocytosis in synaptic vesicles. In retina, STX1A may help in the structural formation of the INL (inner nuclear layer) and OPL(outer plexiform layer). Deletion of STX1A in mice affects the functions of hypothalamic-pituitary-adrenal axis. It may participate in spinal nociceptive plasticity promoted by peripheral nerve injury.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Syntaxin 1 is a membrane protein. It is also known as HPC-1. Neurons express syntaxin 1A.

Immunogen

highly purified GST fusion protein with the residues 1-265 of rat syntaxin 1A (intracellular, N-terminal).

Physical form

After reconstitution, the antibody solution is phosphate buffered saline, pH 7.4, containing 1% BSA and 0.05% sodium azide.

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Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Chronic 3

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

常规特殊物品
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Tiziana Cotrufo et al.
The European journal of neuroscience, 36(9), 3152-3164 (2012-09-06)
Directed cell migration and axonal guidance are essential steps in neural development that share many molecular mechanisms. The guidance of developing axons and migrating neurons is likely to depend on the precise control of plasmalemma turnover in selected regions of
Chronic exercise enhances insulin secretion ability of pancreatic islets without change in insulin content in non-diabetic rats
Tsuchiya M, et al.
Biochemical and Biophysical Research Communications, 430(2), 676-682 (2013)
Impaired NGF/TrkA Signaling Causes Early AD-Linked Presynaptic Dysfunction in Cholinergic Primary Neurons
Latina V, et al.
Frontiers in Cellular Neuroscience, 11 (2017)
SNARE protein expression in synaptic terminals and astrocytes in the adult hippocampus: a comparative analysis
Schubert V, et al.
Glia, 59(10), 1472-1488 (2011)
Syntaxin 1 is expressed in the trout saccular hair cells: RT-PCR and immunocytochemical observations
KM Khan, et al.
Iranian Journal of Pharmaceutical Research : IJPR, 3, 10-10 (2004)

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