S2194
Anti-SNAP-23 (TS-19) antibody produced in rabbit
IgG fraction of antiserum, buffered aqueous solution
Synonym(s):
Anti-Synaptosomal-Associated Protein 23
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About This Item
UNSPSC Code:
12352203
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ARR, IF, WB
Citations:
9
biological source
rabbit
conjugate
unconjugated
antibody form
IgG fraction of antiserum
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 23 kDa
species reactivity
mouse, rat
technique(s)
indirect immunofluorescence: 1:200 using mouse embryonic 3T3-LT cell line., microarray: suitable, western blot: 1:1,000 using whole cell extract of mouse fibroblasts NIH3T3 cell
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... SNAP23(8773)
mouse ... Snap23(20619)
rat ... Snap23(64630)
General description
Anti-SNAP-23 (TS-19) is developed in rabbit using a synthetic peptide corresponding to amino acids, located at the C-terminus, of mouse SNAP-23, conjugated to keyhole limpet hemocyanin (KLH) as immunogen. SNARE proteins are present on both vesicle membranes (vesicle SNAREs or vSNAREs) and on target membranes (target SNAREs or t-SNAREs). SNAP-23 (synaptosomal associated protein, 23 kDa, syndet), is a nonneuronal homolog of SNAP-25, originally identified in a human B-lymphocyte cDNA library in a yeast two-hybrid screen for proteins interacting with syntaxin. SNAP-23 is ubiquitously expressed.
Immunogen
synthetic peptide corresponding to amino acids 203-221 located at the C-terminus of mouse SNAP-23, conjugated to KLH. This sequence is identical in rat and highly conserved (84% identity) in human SNAP-23.
Application
Anti-SNAP-23 (TS-19) antibody produced in rabbit has been used in:
- immunofluorescence
- immunoblotting
- immunoprecipitation
Biochem/physiol Actions
SNAP-23 (synaptosomal associated protein, 23 kDa, syndet) is thought to be a key player in many distinct protein trafficking events in non-neuronal cells. For example, SNAP-23 is involved in diverse protein trafficking events such as glucose transporter type 4 (GLUT-4) trafficking in adipocytes, compound exocytosis in mast cells, polarized protein trafficking, platelet dense core granule release.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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