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S3255

Sterigmatocystin

Name: Sterigmatocystin
Brand: SIGMA

powder, ≥98% (TLC)

Synonym(s):

3a,12c-Dihydro-8-hydroxy-6-methoxy-7H-furol[3′,2′:4,5]furo[2,3-c]xanthen-7-one

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About This Item

Empirical Formula (Hill Notation):

C₁₈H₁₂O₆

CAS Number:

10048-13-2

Molecular Weight:

324.28

UNSPSC Code:

85151701

NACRES:

NA.25

PubChem Substance ID:

24899549

EC Number:

233-158-6

Beilstein/REAXYS Number:

53259

MDL number:

MFCD00005084

Assay:

≥98% (TLC)

Form:

powder

Quality level:

200

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Quality Level

200

assay

≥98% (TLC)

form

powder

color

yellow

storage temp.

−20°C

SMILES string

COc1cc2OC3OC=CC3c2c4Oc5cccc(O)c5C(=O)c14

InChI

1S/C18H12O6/c1-21-11-7-12-13(8-5-6-22-18(8)24-12)17-15(11)16(20)14-9(19)3-2-4-10(14)23-17/h2-8,18-19H,1H3

InChI key

UTSVPXMQSFGQTM-UHFFFAOYSA-N

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Biochem/physiol Actions

Initiates lung and liver tumors under experimental conditions.

pictograms

GHS06,GHS08

signalword

Danger

hcodes

H301,H351

pcodes

P201 - P301 + P310 + P330

Hazard Classifications

Acute Tox. 3 Oral - Carc. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

高风险级别生物产品--毒素类产品

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Certificates of Analysis (COA)

Lot/Batch Number

0000510985

0000452403

0000425139

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Hydrolase controls cellular NAD, sirtuin, and secondary metabolites.

Motoyuki Shimizu et al.

Molecular and cellular biology, 32(18), 3743-3755 (2012-07-18)

Cellular levels of NAD(+) and NADH are thought to be controlled by de novo and salvage mechanisms, although evidence has not yet indicated that they are regulated by NAD(+) degradation. Here we show that the conserved nudix hydrolase isozyme NdxA

Distribution of sterigmatocystin in filamentous fungi.

Christian Rank et al.

Fungal biology, 115(4-5), 406-420 (2011-05-03)

During the last 50y, the carcinogenic mycotoxin sterigmatocystin (ST) has been reported in several phylogenetically and phenotypically different genera: Aschersonia, Aspergillus, Bipolaris, Botryotrichum, Chaetomium, Emericella, Eurotium, Farrowia, Fusarium, Humicola, Moelleriella, Monocillium and Podospora. We have reexamined all available strains of

An Aspergillus nidulans bZIP response pathway hardwired for defensive secondary metabolism operates through aflR.

Wen-Bing Yin et al.

Molecular microbiology, 83(5), 1024-1034 (2012-01-31)

The eukaryotic bZIP transcription factors are critical players in organismal response to environmental challenges. In fungi, the production of secondary metabolites (SMs) is hypothesized as one of the responses to environmental insults, e.g. attack by fungivorous insects, yet little data

Fungal and mycotoxin assessment of dried edible mushroom in Nigeria.

C N Ezekiel et al.

International journal of food microbiology, 162(3), 231-236 (2013-03-05)

In order to determine whether dried mushrooms are a foodstuff that may be less susceptible to infection by toxigenic molds and consequently to mycotoxin contamination, 34 dried market samples were analyzed. Fungal population was determined in the samples by conventional

veA-dependent RNA-pol II transcription elongation factor-like protein, RtfA, is associated with secondary metabolism and morphological development in Aspergillus nidulans.

Vellaisamy Ramamoorthy et al.

Molecular microbiology, 85(4), 795-814 (2012-07-13)

In Aspergillus nidulans the global regulatory gene veA is necessary for the biosynthesis of several secondary metabolites, including the mycotoxin sterigmatocystin (ST). In order to identify additional veA-dependent genetic elements involved in regulating ST production, we performed a mutagenesis on

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Global Trade Item Number

SKU	GTIN
S3255-1MG	04061826017067
S3255-5MG	04061836922023

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