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S3388

Sulforhodamine 101 acid chloride

Technical grade

Synonym(s):

Sulforhodamine 101 sulfonyl chloride

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About This Item

Empirical Formula (Hill Notation):
C31H29ClN2O6S2
CAS Number:
82354-19-6
Molecular Weight:
625.15
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
24899558
MDL number:
MFCD00012406
Beilstein/REAXYS Number:
8667894

Key Documents

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Product Name

Sulforhodamine 101 acid chloride, Technical grade

InChI

1S/C31H29ClN2O6S2/c32-41(35,36)20-9-10-21(26(17-20)42(37,38)39)27-24-15-18-5-1-11-33-13-3-7-22(28(18)33)30(24)40-31-23-8-4-14-34-12-2-6-19(29(23)34)16-25(27)31/h9-10,15-17H,1-8,11-14H2

SMILES string

[O-]S(=O)(=O)c1cc(ccc1C2=C3C=C4CCC[N+]5=C4C(CCC5)=C3Oc6c7CCCN8CCCc(cc26)c78)S(Cl)(=O)=O

InChI key

MPLHNVLQVRSVEE-UHFFFAOYSA-N

form

powder

composition

Dye content, ~75%

impurities

~1 mol/mol chloroform as solvent of crystallization

solubility

methanol: 10 mg/mL

fluorescence

λex 586 nm; λem 605 nm in H2O

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

−20°C

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Application

Sulforhodamine 101 acid chloride has been used in an encapsulated fluorescent probe as a model drug to study drug-delivery properties of rhamnogalacturonan-I based microcapsules. It has also been used in confocal imaging as an astrocyte specific dye.

General description

Sulforhodamine 101 is a red fluorescent dye. It is water-soluble, amphoteric rhodamine. The dye can be specifically used as a marker of astroglia in the neocortex. It is commonly used for brain imaging. Studies suggest that sulforhodamine 101 may be used as an epileptogenic agent.

Other Notes

Mixture of the two monosulfonyl chloride derivatives of sulforhodamine 101.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

易制毒化学品（2类）
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Certificates of Analysis (COA)

Lot/Batch Number
068K3799
058K3784
038K3776
028K1387
117K3780

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Jianfen Luo et al.
The Annals of otology, rhinology, and laryngology, 121(3), 208-216 (2012-04-26)
We examined the distribution of gentamicin sulfate in the inner ear after delivery via a chitosan glycerophosphate (CGP) hydrogel system and examined the change in morphology of the hair cells so as to determine how gentamicin affected the function of
Mitochondrial dysfunction is an important cause of neurological deficits in an inflammatory model of multiple sclerosis
Mona S
Scientific Reports, 63, 33249-33249 (2016)
Rhamnogalacturonan-I Based Microcapsules for Targeted Drug Release
Anna J
PLoS ONE, 11(12), e0168050-e0168050 (2016)
In vivo imaging of oligodendrocytes with sulforhodamine 101
Robert A Hill
Nature Medicine, 11(11), 1081-1082 (2014)
Tian Wang et al.
Cell biochemistry and biophysics, 65(3), 381-398 (2012-10-31)
Loop diuretics such as bumetanide and furosemide enhance aminoglycoside ototoxicity when co-administered to patients and animal models. The underlying mechanism(s) is poorly understood. We investigated the effect of these diuretics on cellular uptake of aminoglycosides, using Texas Red-tagged gentamicin (GTTR)
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Product Information Sheet - S3388

Product Information Sheet

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