S3821
Anti-phospho-Synaptotagmin (Ser309) antibody produced in rabbit
affinity isolated antibody, buffered aqueous glycerol solution
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About This Item
Conjugate:
unconjugated
Clone:
polyclonal
Application:
DB, WB
Citations:
5
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous glycerol solution
usage
sufficient for 10 blots
species reactivity
mouse, human, rat
technique(s)
dot blot: suitable, western blot: 1:1,000 using rat brain lysate
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... SYT1(6857)
mouse ... Syt1(20979)
rat ... Syt1(25716)
General description
SYT1 (synaptotagmin-1) or phospho-Synaptotagmin is a calcium binding synaptic vesicle protein, that is located on chromosome 12q21. It is usually present in nerve cells.
Immunogen
synthetic phosphopeptide corresponding to amino acids residues surrounding the serine 309 of synaptotagmin (Syt).
Biochem/physiol Actions
Synaptotagmin-1 (SYT1) is an essential factor for exocytosis, endocytosis and vesicular Ca2+/H+ antiport activity.
Physical form
Solution in 10 mM HEPES, pH 7.5, 150 mM NaCl with 100 μg/mL BSA and 50% glycerol.
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Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Related Content
Transancestral mapping and genetic load in systemic lupus erythematosus
Langefeld CD, et al.
Nature Communications, 8 (2017)
Identification of a human synaptotagmin-1 mutation that perturbs synaptic vesicle cycling
Baker K, et al.
The Journal of Clinical Investigation, 125(4), 1670-1678 (2015)
Differential Membrane Binding Mechanics of Synaptotagmin Isoforms Observed in Atomic Detail
Vermaas JV and Tajkhorshid E
Biochemistry, 56(1), 281-293 (2017)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| S3821-1VL | 04061835809813 |