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Merck
CN

S3875

Seleno-DL-methionine

≥99% (TLC)

Synonym(s):

2-amino-4-(methylseleno)-Butanoic acid

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About This Item

Empirical Formula (Hill Notation):
C5H11NO2Se
CAS Number:
Molecular Weight:
196.11
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
215-977-0
MDL number:
Beilstein/REAXYS Number:
1758204
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Product Name

Seleno-DL-methionine, ≥99% (TLC)

InChI key

RJFAYQIBOAGBLC-UHFFFAOYSA-N

InChI

1S/C5H11NO2Se/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)

SMILES string

C[Se]CCC(N)C(O)=O

assay

≥99% (TLC)

form

powder

color

white to off-white

application(s)

cell analysis

storage temp.

−20°C

Quality Level

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signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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Susie Shih-Yin Huang et al.
Aquatic toxicology (Amsterdam, Netherlands), 126, 274-282 (2012-10-24)
Selenium (Se) and mercury (Hg) are prevalent pollutants of industrialized watersheds. However, when co-administered, Se has protective effects on organisms from Hg. The mechanism is not fully understood, but it is thought that Se reduces Hg availability, either by forming
Ian R Bothwell et al.
Journal of the American Chemical Society, 134(36), 14905-14912 (2012-08-25)
Posttranslational methylation by S-adenosyl-L-methionine(SAM)-dependent methyltransferases plays essential roles in modulating protein function in both normal and disease states. As such, there is a growing need to develop chemical reporters to examine the physiological and pathological roles of protein methyltransferases. Several
Vasundara Venkateswaran et al.
Cancer research, 62(9), 2540-2545 (2002-05-01)
Prostate cancer (PCA) is the most common histological malignancy and the second leading cause of cancer deaths among North American men. There has been considerable interest in the chemopreventative properties of selenium. In this study, we assessed whether selenium inhibits
Pedro José Barbosa Pereira et al.
Journal of structural biology, 181(2), 89-94 (2012-11-28)
Selenomethionine labeling is the most common technique used in protein crystallography to derivatize recombinant proteins for experimental phasing using anomalous scattering at tunable synchrotron beamlines. Recently, it has been shown that UV radiation depletes electron density of selenium atoms of
Jiankun Duan et al.
Journal of chromatography. A, 1268, 173-179 (2012-11-13)
A new phenylalanine derivative (L-N-(2-hydroxy-propyl)-phenylalanine, L-HP-Phe) was synthesized and its chelate with Cu(II) (Cu(II)-(L-HP-Phe)(2)) was used as the chiral selector for the ligand-exchange (LE) chiral separation of D,L-selenomethionine (SeMet) in selenized yeast samples by micelle electrokinetic capillary chromatography (MEKC). In

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