S4819
Anti-Syntaxin 7 antibody produced in rabbit
IgG fraction of antiserum, buffered aqueous solution
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About This Item
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IF, WB
Citations:
4
biological source
rabbit
Quality Segment
conjugate
unconjugated
antibody form
IgG fraction of antiserum
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 35 kDa
species reactivity
rat
technique(s)
indirect immunofluorescence: 1:500-1:1000 using of rat kidney NRK cell line, western blot: 1:1000-1:2000 using whole cell extract of rat kidney NRK cell line
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
rat ... Stx7(60466)
General description
Syntaxin 7 is a 35kDa protein and is a member of t-Soluble N-ethylmaleimide-sensitive factor activating protein receptor (SNARE) protein family. It is widely expressed in multiple tissues.
Immunogen
synthetic peptide corresponding to amino acids 131-149 located at the mid-region of rat syntaxin 7, conjugated to KLH. This sequence is highly conserved (two amino acid substitutions) in mouse and human syntaxin 7 (~80% identity).
Application
Anti-Syntaxin 7 antibody produced in rabbit has been used in immunoblotting and immunofluorescence.
Biochem/physiol Actions
Syntaxin 7, localized on membrane compartments of late endosomes, facilitates fusion of late endosomes with lysosomes. The protein also helps in lysosomal biogenesis. Mutant syntaxin 7 lacking the transmembrane domain blocks endocytic transport from the early to late endosome. Syntaxin 7 has been described to play an important role during phagocytosis.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
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