Key Documents

View All Documentation

S4939

N-Succinyl-Leu-Leu-Val-Tyr-7-amido-4-trifluoromethylcoumarin

Name: N-Succinyl-Leu-Leu-Val-Tyr-7-amido-4-trifluoromethylcoumarin
Brand: SIGMA

proteasome substrate, ≥98% (HPLC), solid

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₄₀H₅₀N₅O₁₀F₃

Molecular Weight:

817.85

UNSPSC Code:

12352204

PubChem Substance ID:

329824447

NACRES:

NA.32

MDL number:

MFCD03453017

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Product Name

N-Succinyl-Leu-Leu-Val-Tyr-7-amido-4-trifluoromethylcoumarin, ≥98% (HPLC), solid

Quality Level

200

assay

≥98% (HPLC)

form

solid

solubility

DMF: 1 mg/mL, clear, colorless to light yellow

storage temp.

−20°C

SMILES string

CC(C)C[C@H](NC(=O)CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)Nc2ccc3c(OC(=O)C=C3C(F)(F)F)c2

InChI

1S/C40H50F3N5O10/c1-20(2)15-28(45-32(50)13-14-33(51)52)37(55)46-29(16-21(3)4)38(56)48-35(22(5)6)39(57)47-30(17-23-7-10-25(49)11-8-23)36(54)44-24-9-12-26-27(40(41,42)43)19-34(53)58-31(26)18-24/h7-12,18-22,28-30,35,49H,13-17H2,1-6H3,(H,44,54)(H,45,50)(H,46,55)(H,47,57)(H,48,56)(H,51,52)/t28-,29-,30-,35-/m0/s1

InChI key

ZSJPCNKJLSJEQF-DWNBPJMTSA-N

Biochem/physiol Actions

Chymotrypsin and multicatalytic endopeptidase complex: proteasome substrate similar to AMC derivative

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

新产品

This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Upregulation of tRNA-Ser-AGA-2-1 Promotes Malignant Behavior in Normal Bronchial Cells.

Mafalda Santos et al.

Frontiers in molecular biosciences, 9, 809985-809985 (2022-05-20)

Serine tRNAs (tRNASer) are frequently overexpressed in tumors and associated with poor prognosis and increased risk of recurrence in breast cancer. Impairment of tRNA biogenesis and abundance also impacts proteome homeostasis, and activates protein quality control systems. Herein, we aimed

Human cells adapt to translational errors by modulating protein synthesis rate and protein turnover.

Ana Sofia Varanda et al.

RNA biology, 17(1), 135-149 (2019-10-02)

Deregulation of tRNAs, aminoacyl-tRNA synthetases (aaRS) or tRNA modifying enzymes, increase the level of protein synthesis errors (PSE) and are associated with several diseases, but the cause-effect mechanisms of these pathologies remain elusive. To clarify the role of PSE in

Global Trade Item Number

SKU	GTIN
S4939-10MG	04061832910185

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service