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S6377

Sulfisoxazole

≥99.0%

Synonym(s):

4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide, N1-(3,4-Dimethyl-5-isoxazolyl)sulfanilamide, Sulfafurazole

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About This Item

Empirical Formula (Hill Notation):
C11H13N3O3S
CAS Number:
127-69-5
Molecular Weight:
267.30
EC Number:
204-858-9
UNSPSC Code:
12352200
PubChem Substance ID:
24899697
Beilstein/REAXYS Number:
6737262
MDL number:
MFCD00003150
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assay

≥99.0%

solubility

acetone: complete 50 mg/ml, 10% HCl: complete 33 mg/mL, clear, colorless to faintly yellow, alcohol: slightly soluble, chloroform: insoluble

originator

Roche

storage temp.

2-8°C

SMILES string

Cc1noc(NS(=O)(=O)c2ccc(N)cc2)c1C

InChI

1S/C11H13N3O3S/c1-7-8(2)13-17-11(7)14-18(15,16)10-5-3-9(12)4-6-10/h3-6,14H,12H2,1-2H3

InChI key

NHUHCSRWZMLRLA-UHFFFAOYSA-N

Gene Information

rat ... Ednra(24326)

Application

Sulfisoxazole was one of the antibiotics tested on bacterial reporter panel that gave information on pollution load on the environment.11

Biochem/physiol Actions

Sulfisoxazole, a sulfonamide, is an antibacterial agent that acts by inhibiting the folic acid metabolism.1 It is also a non-selective endothelin antagonist. It is effective in the treatment of recurrent acute otitis media and also in rendering protection to retina against ischemic-like insults.2,3

Features and Benefits

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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