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S6626

Strophanthidin

cardiotonic steroid

Synonym(s):

3β,5,14-Trihydroxy-19-oxo-5β,20(22)-cardenolide, Apocymarin, Convallatoxigenin, Corchorin, Corchoside A aglycone, Corchsularin, Cymarigenen, Erysimupicrone, K-Strophanthidin

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About This Item

Empirical Formula (Hill Notation):
C23H32O6
CAS Number:
66-28-4
Molecular Weight:
404.50
NACRES:
NA.77
PubChem Substance ID:
24899714
UNSPSC Code:
12352200
EC Number:
200-626-6
MDL number:
MFCD00046266
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Product Name

Strophanthidin,

Quality Segment

100

storage temp.

−20°C

SMILES string

C[C@@]12[C@@](CC[C@@H]2C(CO3)=CC3=O)(O)[C@]4([H])CC[C@]5(O)C[C@@H](O)CC[C@]5(C([H])=O)[C@@]4([H])CC1

InChI

1S/C23H32O6/c1-20-6-3-17-18(4-8-22(27)11-15(25)2-7-21(17,22)13-24)23(20,28)9-5-16(20)14-10-19(26)29-12-14/h10,13,15-18,25,27-28H,2-9,11-12H2,1H3

InChI key

ODJLBQGVINUMMR-UHFFFAOYSA-N

Application

Strophanthidin was used to synthesize acetylstrophanthidin and the effect on neurotransmitter release from dog saphenous vein was studied.3

Biochem/physiol Actions

Strophanthidin is a cardiotonic steroid that elevates the activity of Na+/K+-ATPase in cardiac myocytes.1 It decreases the potassium content and raises the sodium content in rabbit renal cortex slices.2

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pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 1 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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