S6701
SF-11
≥98% (HPLC)
Synonym(s):
N-(4-Ethoxyphenyl)-4-(hydroxydiphenylmethyl)-1-piperidinecarbothioamide, SID 17507305
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About This Item
Empirical Formula (Hill Notation):
C27H30N2O2S
CAS Number:
Molecular Weight:
446.60
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
assay
≥98% (HPLC)
form
powder
color
white to off-white
solubility
DMSO: ≥20 mg/mL
storage temp.
2-8°C
SMILES string
CCOc1ccc(NC(=S)N2CCC(CC2)C(O)(c3ccccc3)c4ccccc4)cc1
InChI
1S/C27H30N2O2S/c1-2-31-25-15-13-24(14-16-25)28-26(32)29-19-17-23(18-20-29)27(30,21-9-5-3-6-10-21)22-11-7-4-8-12-22/h3-16,23,30H,2,17-20H2,1H3,(H,28,32)
InChI key
PMEQBGAGFZDWQX-UHFFFAOYSA-N
Application
SF-11 may be used in NPY Y2 receptor-mediated studies.
Biochem/physiol Actions
Radioligand studies reveal that SF-11 also targets 5-HT2B and dopamine transporter.1
SF-11 is a potent, selective NPY Y2 receptor antagonist; brain-penetrant.
Features and Benefits
This compound is featured on the Neuropeptide Y Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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