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S6942

Staurosporine solution from Streptomyces sp.

Name: Staurosporine solution from <i>Streptomyces </i>sp.
Brand: SIGMA

Ready Made Solution, 1 mM in DMSO (100 μg/214 μL)

Synonym(s):

Antibiotic AM-2282

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About This Item

UNSPSC Code:

12352200

NACRES:

NA.77

EC Number:

200-664-3

MDL number:

MFCD04041131

Assay:

>98% (HPLC)

Quality level:

300

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Properties

Product Name

Staurosporine solution from Streptomyces sp., Ready Made Solution, 1 mM in DMSO (100 μg/214 μL)

Quality Level

300

assay

>98% (HPLC)

concentration

1 mM in DMSO (100 μg/214 μL)

technique(s)

cell culture | mammalian: suitable

antibiotic activity spectrum

fungi

mode of action

enzyme | inhibits

shipped in

wet ice

storage temp.

−20°C

Description

General description

Chemical structure: indol derivative

Application

Staurosporine solution from Streptomyces sp. was used to study the effect of PKC inhibition on signaling mediated by angiotensin II.³ It was used to induce cell death in Jurkat cells.⁴

Biochem/physiol Actions

Potent cell-permeable inhibitor of protein kinase C. Induces apoptosis in Jurkat cells.

Potent inhibitor of phospholipid/calcium-dependent protein kinase. Inhibits the upregulation of VEGF expression in tumor cells.

Storage Class

10 - Combustible liquids

flash_point_f

188.6 °F - closed cup

flash_point_c

87 °C - closed cup

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number

0000436149

0000411505

0000209974

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Global Trade Item Number

SKU	GTIN
S6942-100UL	04061837899089
S6942-200UL	04061836959708
S6942-110UL	04061837899096