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S7001

Strychnine hemisulfate salt

≥98.0%, suitable for ligand binding assays and NMR

Synonym(s):

Strychnidin-10-one sulfate (2:1)

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About This Item

Linear Formula:
C21H22N2O2 · 1/2H2SO4
CAS Number:
60-41-3
Molecular Weight:
383.45
NACRES:
NA.26
PubChem Substance ID:
329824573
UNSPSC Code:
12352210
EC Number:
200-477-7
MDL number:
MFCD00068328
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Product Name

Strychnine hemisulfate salt,

assay

≥98.0%

Quality Level

100

form

powder

technique(s)

NMR: suitable, ligand binding assay: suitable

color

white to off-white

SMILES string

OS(O)(=O)=O.O=C1C[C@@H]2OCC=C3CN4CC[C@@]56[C@@H]4C[C@@H]3[C@@H]2[C@@H]5N1c7ccccc67.O=C8C[C@@H]9OCC=C%10CN%11CC[C@@]%12%13[C@@H]%11C[C@@H]%10[C@@H]9[C@@H]%12N8c%14ccccc%13%14

InChI

1S/2C21H22N2O2.H2O4S/c2*24-18-10-16-19-13-9-17-21(6-7-22(17)11-12(13)5-8-25-16)14-3-1-2-4-15(14)23(18)20(19)21;1-5(2,3)4/h2*1-5,13,16-17,19-20H,6-11H2;(H2,1,2,3,4)/t2*13-,16-,17-,19-,20-,21+;/m00./s1

InChI key

GOOCRIHPADOQAS-ZNUXJMJHSA-N

Biochem/physiol Actions

Convulsant; glycine receptor antagonist not associated with the NMDA receptor.

pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

Hazard Classifications

Acute Tox. 1 Oral - Acute Tox. 2 Inhalation - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

涉药品监管产品

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Certificates of Analysis (COA)

Lot/Batch Number
0000157345
0000093021
0000082933
0000080435

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Related Content

Product Information Sheet - S7001

Product Information Sheet

Rong-Qing Chen et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 36(9), 1948-1958 (2011-05-20)
Glycine in the hippocampus can exert its effect on both synaptic NMDA receptors (NMDARs) and extrasynaptic functional glycine receptors (GlyRs) via distinct binding sites. Previous studies have reported that glycine induces long-term potentiation (LTP) through the activation of synaptic NMDARs.
Adam C Roberts et al.
PloS one, 14(4), e0214374-e0214374 (2019-04-05)
Zebrafish larvae have several biological features that make them useful for cellular investigations of the mechanisms underlying learning and memory. Of particular interest in this regard is a rapid escape, or startle, reflex possessed by zebrafish larvae; this reflex, the
Mari Hondo et al.
PloS one, 6(9), e25076-e25076 (2011-09-29)
Glycine, a nonessential amino-acid that acts as an inhibitory neurotransmitter in the central nervous system, is currently used as a dietary supplement to improve the quality of sleep, but its mechanism of action is poorly understood. We confirmed the effects
View All Related Papers

Global Trade Item Number

SKUGTIN
S7001-5G04061836959722
S7001-100G04061832726809
S7001-25G04061836959715