Skip to Content
Merck
CN

Key Documents

View All Documentation

S7388

N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide

Subtilisin substrate

Synonym(s):

N-Succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide, N-Succinyl-Ala-Ala-Pro-Phe-pNA

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C30H36N6O9
CAS Number:
70967-97-4
Molecular Weight:
624.64
NACRES:
NA.32
PubChem Substance ID:
24899742
UNSPSC Code:
12352200
MDL number:
MFCD00077161
Beilstein/REAXYS Number:
4289896
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide,

Quality Segment

300

storage temp.

−20°C

SMILES string

[H][C@]1(CCCN1C(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)CCC(O)=O)C(=O)N[C@@H](Cc2ccccc2)C(=O)Nc3ccc(cc3)[N+]([O-])=O

InChI

1S/C30H36N6O9/c1-18(31-25(37)14-15-26(38)39)27(40)32-19(2)30(43)35-16-6-9-24(35)29(42)34-23(17-20-7-4-3-5-8-20)28(41)33-21-10-12-22(13-11-21)36(44)45/h3-5,7-8,10-13,18-19,23-24H,6,9,14-17H2,1-2H3,(H,31,37)(H,32,40)(H,33,41)(H,34,42)(H,38,39)/t18-,19-,23-,24-/m0/s1

InChI key

LKDMKWNDBAVNQZ-WJNSRDFLSA-N

Gene Information

human ... FKBP10(60681)

General description

N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide is a colorimetric substrate for chymotrypsin, human leukocyte cathepsin G and peptidyl prolyl isomerase.

Application

N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide has been used as a substrate to determine chymotrypsin activity.
N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide has been used:
  • as a substrate for cathepsin G assay in bone marrow lysates.
  • in proteolytic activity assay of serine protease subtilisin carlsberg (SC).
  • as a substrate for neutrophil elastase, trypsin and chymotrypsin in protease assay.

Biochem/physiol Actions

N-succinyl-Ala-Ala-Pro-Phe p-nitroanilide is a substrate for subtilisin and proteases.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library