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S8776

Sigma-Aldrich

Sodium chloride solution

0.9% in water, BioXtra, suitable for cell culture

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Linear Formula:
NaCl
CAS Number:
7647-14-5
Molecular Weight:
58.44
Beilstein:
3534976
MDL number:
MFCD00003477
PubChem Substance ID:
24899816
NACRES:
NA.75

sterility

sterile-filtered

Quality Level

200

product line

BioXtra

concentration

0.9% in water

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

SMILES string

[Na+].[Cl-]

InChI

1S/ClH.Na/h1H;/q;+1/p-1

InChI key

FAPWRFPIFSIZLT-UHFFFAOYSA-M

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General description

Sodium chloride is widely used in biochemistry and molecular biology research. It is a component of phosphate buffered saline (Product No. P3813) and βC buffer (Product Nos. S0902 and S8015). Sodium chloride is a component of all media formulations. This product has been qualified for use in preparation of in vitro solutions.

Application

Sodium chloride solution has been used:
  • for intraperitoneal administration in mice to investigate the effect of toll-like receptors (TLR-3) activation on neonatal hypoxic-ischemic (HI)
  • to dissolve bleomycin sulfate for bleomycin treatments in mice
  • to dilute tribromoethanol for intraperitoneal injection in mice

Packaging

PET bottle (100 ml), PETG bottle (20 ml), with caps

Preparation Note

Prepared in tissue culture grade water.

Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Laurent Dortet et al.
Journal of clinical microbiology, 52(7), 2359-2364 (2014-04-25)
Multidrug-resistant Acinetobacter baumannii isolates, particularly those that produce carbapenemases, are increasingly reported worldwide. The biochemically based Carba NP test, extensively validated for the detection of carbapenemase producers among Enterobacteriaceae and Pseudomonas spp., has been modified to detect carbapenemase production in
Francis Kim et al.
JAMA, 311(1), 45-52 (2013-11-19)
Hospital cooling improves outcome after cardiac arrest, but prehospital cooling immediately after return of spontaneous circulation may result in better outcomes. To determine whether prehospital cooling improves outcomes after resuscitation from cardiac arrest in patients with ventricular fibrillation (VF) and
I Dzneladze et al.
Leukemia, 29(7), 1485-1495 (2015-03-05)
In this study, we investigated the role of inositol polyphosphate-4-phosphatase, type-II (INPP4B) in acute myeloid leukemia (AML). We observed that AML patients with high levels of INPP4B (INPP4B(high)) had poor response to induction therapy, shorter event-free survival and shorter overall
Frédéric Lebrun-Julien et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(25), 8432-8448 (2014-06-21)
The mammalian target of rapamycin (mTOR) pathway integrates multiple signals and regulates crucial cell functions via the molecular complexes mTORC1 and mTORC2. These complexes are functionally dependent on their raptor (mTORC1) or rictor (mTORC2) subunits. mTOR has been associated with
Koji Tanaka et al.
Nature communications, 6, 6337-6337 (2015-02-27)
Pore-forming toxins (PFT) are water-soluble proteins that possess the remarkable ability to self-assemble on the membrane of target cells, where they form pores causing cell damage. Here, we elucidate the mechanism of action of the haemolytic protein fragaceatoxin C (FraC)
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