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S9666

Sphingosine 1-phosphate

Name: Sphingosine 1-phosphate
Brand: SIGMA

≥95% (TLC), powder, lipid second messenger

Synonym(s):

(2S,3R,4E)-2-Amino-4-octadecene-1,3-diol 1-phosphate, D-erythro-Sphingosine 1-phosphate

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About This Item

Empirical Formula (Hill Notation):

C₁₈H₃₈NO₅P

CAS Number:

26993-30-6

Molecular Weight:

379.47

UNSPSC Code:

12352211

PubChem Substance ID:

24899853

NACRES:

NA.77

MDL number:

MFCD00270077

Assay:

≥95%

Form:

powder

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Properties

Product Name

Sphingosine 1-phosphate, ≥95%, powder

Quality Segment

300

assay

≥95%

form

powder

storage temp.

−20°C

SMILES string

CCCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](N)COP(O)(O)=O

InChI

1S/C18H38NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(20)17(19)16-24-25(21,22)23/h14-15,17-18,20H,2-13,16,19H2,1H3,(H2,21,22,23)/b15-14+/t17-,18+/m0/s1

InChI key

DUYSYHSSBDVJSM-KRWOKUGFSA-N

Gene Information

human ... S1PR1(1901), S1PR2(9294), S1PR3(1903), S1PR4(8698), S1PR5(53637)

Description

Biochem/physiol Actions

A lipid second messenger that binds to S1P₁ and S1P₃ receptors. Mobilizes intracellular Ca²⁺ stores and decreases cellular cAMP. Activates phospholipase D. S1P stimulates the migration of endothelial cells but inhibits the migration of other cell types. Induces angiogenesis.

Features and Benefits

This compound is featured on the Lysophospholipid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number

0000488213

0000431191

0000415546

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Articles

Discover Bioactive Small Molecules for Lipid Signaling Research

Global Trade Item Number

SKU	GTIN
S9666-1MG	04061836961633