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S9944

Sibutramine hydrochloride monohydrate

≥98% (HPLC), solid

Synonym(s):

1-(4-Chlorophenyl)-N,N-dimethyl-alpha-(2-methylpropyl)cyclobutanemethanamine hydrochloride monohydrate, Meridia, Reductil

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About This Item

Empirical Formula (Hill Notation):
C17H26ClN · HCl
CAS Number:
84485-00-7
Molecular Weight:
316.31
NACRES:
NA.77
PubChem Substance ID:
329824638
UNSPSC Code:
12352116
MDL number:
MFCD04039806
Assay:
≥98% (HPLC)
Form:
solid
Storage condition:
desiccated
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Quality Segment

100

assay

≥98% (HPLC)

form

solid

drug control

USDEA Schedule IV

storage condition

desiccated

color

white

solubility

DMSO: >30 mg/mL, H2O: insoluble

originator

Abbott

storage temp.

room temp

SMILES string

O.Cl.CC(C)CC(N(C)C)C1(CCC1)c2ccc(Cl)cc2

InChI

1S/C17H26ClN.ClH.H2O/c1-13(2)12-16(19(3)4)17(10-5-11-17)14-6-8-15(18)9-7-14;;/h6-9,13,16H,5,10-12H2,1-4H3;1H;1H2

InChI key

KFNNPQDSPLWLCX-UHFFFAOYSA-N

Gene Information

human ... SLC6A2(6530), SLC6A3(6531), SLC6A4(6532)

Application

Sibutramine hydrochloride monohydrate was used as standard to screen dietary supplements for sibutramine using ion mobility spectrometer.1

Biochem/physiol Actions

Sibutramine is a serotonin and noradrenaline reuptake inhibitor (SNRI).
Sibutramine is a serotonin and noradrenaline reuptake inhibitor (SNRI). It is an antiobesity drug, which decreases calorie intake and increases energy expanditure. Sibutramine antagonizes MPTP-induced dopamine depletion in mouse brain.

Features and Benefits

This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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