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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i)
Citations:
-
biological source
rabbit
conjugate
unconjugated
antibody form
IgG fraction of antiserum
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
Epstein-Barr virus
technique(s)
indirect ELISA: 1:1000
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Related Categories
General description
Epstein-Barr BGLF4 plays many key roles by phosphorylating several proteins including the viral DNA processivity factor BMRF1, EBNA1 or EBNA2. It is required for efficient lytic DNA replication and release of nucleocapsids from the nucleus. This protein contributes to the compaction of host cell chromatin in cells undergoing lytic replication, presumably by phosphorylating the host condensin complex and host TOP2A. BGLF4 induces disassembly of the nuclear lamina by phosphorylating with host LMNA, and phosphorylates substrates involved in capsid assembly and DNA packaging. It facilitates the switch from latent to lytic DNA replication by down-regulating EBNA1 replication function. This protein phosphorylates the viral immediate-early protein BZLF1.
Immunogen
BGL (1-30)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of Epstein-Barr BGLF4 Kinase.
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of Epstein-Barr BGLF4 Kinase.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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