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SAB1300496

Anti-Rat MKP3 antibody produced in rabbit

Name: Anti-Rat MKP3 antibody produced in rabbit
Brand: SIGMA

IgG fraction of antiserum, buffered aqueous solution

Synonym(s):

Anti-Mitogen-activated protein kinase phosphatase 3, MAP kinase phosphatase 3, MKP-3

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About This Item

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ELISA (i)

Citations:

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Properties

biological source

rabbit

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

technique(s)

indirect ELISA: 1:1000

NCBI accession no.

NP_446335

UniProt accession no.

Q64346

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Description

General description

Dual specificity protein tyrosine phosphatases (dsPTPs) are a subfamily of protein tyrosine phosphatases implicated in the regulation of mitogen-activated protein kinase (MAPK). MKP-1 (also known as CL100, 3CH134, Erp, and hVH-1) exemplifies a class of dual-specificity phosphatase able to reverse the activation of MAP kinases by dephosphorylating critical tyrosine and threonine residues. MKP-3 is 36% identical to MKP-1 and it blocks both the phosphorylation and enzymatic activation of ERK2 by mitogens. MKP-3 mRNA is expressed in lung, heart, brain, and kidney, but not significantly in skeletal muscle or testis

Immunogen

RAT MKP3 (1-410)
This antibody is generated from rabbits immunized with a 6xHIS-tagged recombinant protein encoding aa 1-381 of rat MKP3.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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Storage Class

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品

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Certificates of Analysis (COA)

Lot/Batch Number

020M2034

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Global Trade Item Number

SKU	GTIN
SAB1300496-100UG	04061831470093