SAB1309014
Anti-phospho-mouse TSC1(S555) antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
Synonym(s):
Hamartin, Tuberous sclerosis 1 protein homolog, Tsc1, Kiaa0243
biological source
(Mouse)
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
form
liquid
mol wt
158969Da
species reactivity
mouse
technique(s)
dot blot: 1:500
isotype
IgG
NCBI accession no.
storage temp.
-10 to -25°C
target post-translational modification
phosphorylation (pSer555), phosphorylation (pSer555)
Gene Information
mouse ... Tsc1(64930)
General description
In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
Biochem/physiol Actions
This mouse TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S555 of mouse TSC1.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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