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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
6E8, monoclonal
Application:
ELISA (c), ELISA (i), IF, WB
Citations:
4
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
6E8, monoclonal
form
buffered aqueous solution
mol wt
antigen ~43.9 kDa
species reactivity
human
technique(s)
capture ELISA: suitable, immunofluorescence: suitable, indirect ELISA: suitable, western blot: 1-5 μg/mL
isotype
IgG2aκ
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... ANKRD37(353322)
Related Categories
General description
Ankyrin repeat domain 37 (ANKRD37) is a protein containing ankyrin repeats (ARs) and a nuclear localization signal (NLS). The protein is expressed in human testis, small intestine, colon, blood leukocytes and human pancreatic adenocarcinoma cells. The gene is located on human chromosome 4q35.1.
Immunogen
ANKRD37 (NP_859077.1, 1 a.a. ~ 158 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MLLLDCNPEVDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFLTTIKCMQTIKASEHPDRNDCVAVLRQKRSLGSVENTSGKRKC
Sequence
MLLLDCNPEVDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFLTTIKCMQTIKASEHPDRNDCVAVLRQKRSLGSVENTSGKRKC
Biochem/physiol Actions
Ankyrin repeat domain 37 (ANKRD37) is important in protein-protein interactions and signalling pathways. It acts as a target gene for hypoxia-inducible factor 1 (HIF-1).
Physical form
Solution in phosphate buffered saline, pH 7.4
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Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
常规特殊物品
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Find documentation for the products that you have recently purchased in the Document Library.
Molecular cloning and characterization of a novel human gene containing 4 ankyrin repeat domains
Li J, et al.
Cellular & Molecular Biology Letters, 10(1), 185-193 (2005)
An integrative genomics approach identifies Hypoxia Inducible Factor-1 (HIF-1)-target genes that form the core response to hypoxia
Benita Y, et al.
Nucleic Acids Research, 37(14), 4587-4602 (2009)
Analysis of loss of heterozygosity on chromosome 4q in hepatocellular carcinoma using high-throughput SNP array
Zhang H, et al.
Oncology Reports, 23(2), 445-455 (2010)
Mouse Fem1b interacts with and induces ubiquitin-mediated degradation of Ankrd37
Shi YQ, et al.
Gene, 485(2), 153-159 (2011)
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