SAB1405562
Anti-CAT antibody produced in mouse
purified immunoglobulin, buffered aqueous solution
Synonym(s):
MGC138422, MGC138424
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
indirect immunofluorescence
western blot
western blot
Species reactivity:
human
Citations:
6
Technique(s):
indirect immunofluorescence: suitable
western blot: 1 μg/mL
western blot: 1 μg/mL
Uniprot accession no.:
Product Name
Anti-CAT antibody produced in mouse, purified immunoglobulin, buffered aqueous solution
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen ~59.8 kDa
species reactivity
human
technique(s)
indirect immunofluorescence: suitable
western blot: 1 μg/mL
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... CAT(847)
Biochem/physiol Actions
Catalase (CAT) protects different cell types from the harmful effects of hydrogen peroxide. It is involved in idiopathic male infertility. CAT converts hydrogen peroxide to water and molecular oxygen. CAT promotes resistance against many diseases. Mutations in CAT is linked to acatalasemia.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Catalase (CAT) is an antioxidant enzyme. CAT gene is located on human chromosome 11p13. CAT is present in peroxisomes of most aerobic organisms. It is a heme enzyme expressed mainly in liver.
Immunogen
CAT (NP_001743.1, 1 a.a. ~ 527 a.a) full-length human protein.
Sequence
MADSRDPASDQMQHWKEQRAAQKADVLTTGAGNPVGDKLNVITVGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITKYSKAKVFEHIGKKTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDPILFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLSVEDAARLSQEDPDYGIRDLFNAIATGKYPSWTFYIQVMTFNQAETFPFNPFDLTKVWPHKDYPLIPVGKLVLNRNPVNYFAEVEQIAFDPSNMPPGIEASPDKMLQGRLFAYPDTHRHRLGPNYLHIPVNCPYRARVANYQRDGPMCMQDNQGGAPNYYPNSFGAPEQQPSALEHSIQYSGEVRRFNTANDDNVTQVRAFYVNVLNEEQRKRLCENIAGHLKDAQIFIQKKAVKNFTEVHPDYGSHIQALLDKYNAEKPKNAIHTFVQSGSHLAAREKANL
Sequence
MADSRDPASDQMQHWKEQRAAQKADVLTTGAGNPVGDKLNVITVGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITKYSKAKVFEHIGKKTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDPILFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLSVEDAARLSQEDPDYGIRDLFNAIATGKYPSWTFYIQVMTFNQAETFPFNPFDLTKVWPHKDYPLIPVGKLVLNRNPVNYFAEVEQIAFDPSNMPPGIEASPDKMLQGRLFAYPDTHRHRLGPNYLHIPVNCPYRARVANYQRDGPMCMQDNQGGAPNYYPNSFGAPEQQPSALEHSIQYSGEVRRFNTANDDNVTQVRAFYVNVLNEEQRKRLCENIAGHLKDAQIFIQKKAVKNFTEVHPDYGSHIQALLDKYNAEKPKNAIHTFVQSGSHLAAREKANL
Physical form
Solution in phosphate buffered saline, pH 7.4
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Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
常规特殊物品
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A novel catalase mutation (a GA insertion) causes the Hungarian type of acatalasemia
Goth L , et al.
Blood Cells, Molecules and Diseases, 26(2) (2000)
Regulation of catalase expression in healthy and cancerous cells
Glorieux C, et al.
Free Radical Biology & Medicine, 87(3) (2015)
The role of catalase C262T gene polymorphism in the susceptibility and survival of cancers
Wang C, et al.
Scientific Reports, 6(5), 26973-26973 (2016)
Association of CAT--262C/T with the concentration of catalase in seminal plasma and the risk for male infertility in Algeria
Bousnane N, et al.
Systems Biology in Reproductive Medicine, 63(5) (2017)
Structure and heme environment of beef liver catalase at 2.5 A resolution
Reid T, et al.
Proceedings of the National Academy of Sciences of the USA, 78(8) (1981)
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