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Merck
CN

SAB1408057

Sigma-Aldrich

Anti-ARPC5L antibody produced in mouse

purified immunoglobulin, buffered aqueous solution

Synonym(s):

ARC16-2, MGC3038

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
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biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~16.9 kDa

species reactivity

human

technique(s)

western blot: 1 μg/mL

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ARPC5L(81873)

Immunogen

ARPC5L (NP_112240.1, 1 a.a. ~ 153 a.a) full-length human protein.

Sequence
MARNTLSSRFRRVDIDEFDENKFVDEQEEAAAAAAEPGPDPSEVDGLLRQGDMLRAFHAALRNSPVNTKNQAVKERAQGVVLKVLTNFKSSEIEQAVQSLDRNGVDLLMKYIYKGFEKPTENSSAVLLQWHEKALAVGGLGSIIRVLTARKTV

Application

Anti-ARPC5L antibody produced in mouse is suitable for western blot assay.

Biochem/physiol Actions

ARPC5L (Actin related protein 2/3 complex subunit 5-like) is a conserved subunit of multiprotein Arp2/3 complex mainly involved in the formation of actin filament network during different cellular processes. The complex triggers the nucleation and organizes the actin filaments network. It also controls the lamellipodia dependent cellular motility.

Physical form

Solution in phosphate buffered saline, pH 7.4

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Jasmine V G Abella et al.
Nature cell biology, 18(1), 76-86 (2015-12-15)
The Arp2/3 complex consists of seven evolutionarily conserved subunits (Arp2, Arp3 and ARPC1-5) and plays an essential role in generating branched actin filament networks during many different cellular processes. In mammals, however, the ARPC1 and ARPC5 subunits are each encoded
Giulia Bernardini et al.
Molecular bioSystems, 10(6), 1305-1312 (2014-03-13)
Osteosarcoma (OS) is a highly malignant bone tumour, affecting mainly children and young adults between 10 and 20 years of age. It represents the most frequent primitive malignant tumour of the skeletal system and is characterized by an extremely aggressive

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