SAB1408057
Anti-ARPC5L antibody produced in mouse
purified immunoglobulin, buffered aqueous solution
Synonym(s):
ARC16-2, MGC3038
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
2
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen ~16.9 kDa
species reactivity
human
technique(s)
western blot: 1 μg/mL
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... ARPC5L(81873)
Immunogen
ARPC5L (NP_112240.1, 1 a.a. ~ 153 a.a) full-length human protein.
Sequence
MARNTLSSRFRRVDIDEFDENKFVDEQEEAAAAAAEPGPDPSEVDGLLRQGDMLRAFHAALRNSPVNTKNQAVKERAQGVVLKVLTNFKSSEIEQAVQSLDRNGVDLLMKYIYKGFEKPTENSSAVLLQWHEKALAVGGLGSIIRVLTARKTV
Sequence
MARNTLSSRFRRVDIDEFDENKFVDEQEEAAAAAAEPGPDPSEVDGLLRQGDMLRAFHAALRNSPVNTKNQAVKERAQGVVLKVLTNFKSSEIEQAVQSLDRNGVDLLMKYIYKGFEKPTENSSAVLLQWHEKALAVGGLGSIIRVLTARKTV
Application
Anti-ARPC5L antibody produced in mouse is suitable for western blot assay.
Biochem/physiol Actions
ARPC5L (Actin related protein 2/3 complex subunit 5-like) is a conserved subunit of multiprotein Arp2/3 complex mainly involved in the formation of actin filament network during different cellular processes. The complex triggers the nucleation and organizes the actin filaments network. It also controls the lamellipodia dependent cellular motility.
Physical form
Solution in phosphate buffered saline, pH 7.4
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Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Giulia Bernardini et al.
Molecular bioSystems, 10(6), 1305-1312 (2014-03-13)
Osteosarcoma (OS) is a highly malignant bone tumour, affecting mainly children and young adults between 10 and 20 years of age. It represents the most frequent primitive malignant tumour of the skeletal system and is characterized by an extremely aggressive
Jasmine V G Abella et al.
Nature cell biology, 18(1), 76-86 (2015-12-15)
The Arp2/3 complex consists of seven evolutionarily conserved subunits (Arp2, Arp3 and ARPC1-5) and plays an essential role in generating branched actin filament networks during many different cellular processes. In mammals, however, the ARPC1 and ARPC5 subunits are each encoded
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