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SAB1408703

Anti-CENPP antibody produced in rabbit

Name: Anti-CENPP antibody produced in rabbit
Brand: SIGMA

purified immunoglobulin, buffered aqueous solution

Synonym(s):

CENP-P, FLJ33928

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About This Item

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

polyclonal

Application:

Citations:

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Properties

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~33.2 kDa

species reactivity

mouse, human

technique(s)

western blot: 1 μg/mL

NCBI accession no.

NM_001012267.1

UniProt accession no.

Q6IPU0

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CENPP(401541)

Description

General description

CENPP is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006 [PubMed 16622420]).[supplied by OMIM

Immunogen

CENPP (NP_001012267.1, 1 a.a. ~ 288 a.a) full-length human protein.

Sequence
MDAELAEVRALQAEIAALRRACEDPPAPWEEKSRVQKSFQAIHQFNLEGWKSSKDLKNQLGHLESELSFLSTLTGINIRNHSKQTEDLTSTEMTEKSIRKVLQRHRLSGNCHMVTFQLEFQILEIQNKERLSSAVTDLNIIMEPTECSELSEFVSRAEERKDLFMFFRSLHFFVEWFEYRKRTFKHLKEKYPDAVYLSEGPSSCSMGIRSASRPGFELVIVWRIQIDEDGKVFPKLDLLTKVPQRALELDKNRAIETAPLSFRTLVGLLGIEAALESLIKSLCAEENN

Application

Anti-CENPP antibody produced in rabbit is suitable for western blot applications.

Biochem/physiol Actions

CENPP (Centromere protein P) is located on chromosome 9. It is expressed in the centromere/kinetochore components. It is involved in the regulation of mitosis.

Physical form

Solution in phosphate buffered saline, pH 7.4

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品

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Certificates of Analysis (COA)

Lot/Batch Number

09056

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Identification of novel mitosis regulators through data mining with human centromere/kinetochore proteins as group queries.

Aaron R Tipton et al.

BMC cell biology, 13, 15-15 (2012-06-21)

Proteins functioning in the same biological pathway tend to be transcriptionally co-regulated or form protein-protein interactions (PPI). Multiple spatially and temporally regulated events are coordinated during mitosis to achieve faithful chromosome segregation. The molecular players participating in mitosis regulation are

Epigenetic silencing of HIV-1 by the histone H3 lysine 27 methyltransferase enhancer of Zeste 2.

Julia Friedman et al.

Journal of virology, 85(17), 9078-9089 (2011-07-01)

Latent HIV proviruses are silenced as the result of deacetylation and methylation of histones located at the viral long terminal repeat (LTR). Inhibition of histone deacetylases (HDACs) leads to the reemergence of HIV-1 from latency, but the contribution of histone

Global Trade Item Number

SKU	GTIN
SAB1408703-100UG	04061831493795