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Merck
CN

SAB1413282

Sigma-Aldrich

Monoclonal Anti-SEC24A antibody produced in mouse

clone 4D9, purified immunoglobulin, buffered aqueous solution

Synonym(s):

SEC24A

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About This Item

UNSPSC Code:
51111800
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conjugate

unconjugated

Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

4D9, monoclonal

form

buffered aqueous solution

mol wt

35.64 kDa

species reactivity

human

concentration

~0.3-1 μg/μL (Please refer to lot specific concentration)

technique(s)

ELISA: suitable
western blot: suitable

isotype

IgG2a, kappa

Protein ID accession no.

XM_094581

shipped in

dry ice

storage temp.

-10 to -25°C

target post-translational modification

unmodified

Gene Information

human ... SEC24A(10802)

General description

Mouse monoclonal antibody raised against a partial recombinant SEC24A.

Immunogen

SEC24A (XP_094581.5, 301 a.a. ~ 390 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Physical form

Solution in phosphate buffered saline, pH 7.4

Preparation Note

Purification by Protein A sepharose
Storage Instruction: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Other Notes

PLTSSYRDVPQPLFNSAVNQEGITSNTNNGSMVVHSSYDEIEGGGLLATPQLTNKNPKMSRSVGYSYPSLPPGYQNTTPPGATGVPPSSL

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Shi-Jun Deng et al.
Biochimica et biophysica acta. Molecular and cell biology of lipids, 1865(6), 158660-158660 (2020-02-15)
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a secretory protein that promotes low-density lipoprotein receptor (LDLR) degradation and thereby regulating plasma levels of LDL cholesterol. Previous studies have revealed the role of the C-terminal domain (CTD) of PCSK9 in its

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