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SAB2100044

Sigma-Aldrich

Anti-ACVR1C antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-ACVRLK7, Anti-ALK7, Anti-Activin A receptor, type IC

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50 μL
CN¥3,838.85
200 μL
CN¥8,291.56

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

CN¥3,838.85

Estimated to ship onDecember 05, 2025Details

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biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

55 kDa

species reactivity

horse, human, rabbit, bovine

concentration

0.5 mg - 1 mg/mL

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Anti-Potassium Channel Kv1.2 Antibody, clone K14/16 clone K14/16, from mouse

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MABN77

Anti-Potassium Channel Kv1.2 Antibody, clone K14/16

antibody form

affinity purified immunoglobulin

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

purified antibody

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

mouse

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

100

Gene Information

human ... KCNA3(3738)

Gene Information

human ... KCNA3(3738)
mouse ... Kcna3(16491)
rat ... Kcna3(29731)

Gene Information

human ... KCNC2(3747)

Gene Information

human ... KCNA2(3737)

clone

polyclonal

clone

polyclonal

clone

polyclonal

clone

K14/16, monoclonal

technique(s)

immunohistochemistry: suitable, western blot: suitable

technique(s)

flow cytometry: 0.5-5 μg/test using Jurkat T-cells, western blot: 1:200-1:500 using rat brain membranes

technique(s)

ELISA: 1:10000, immunohistochemistry: 1:50-1:100, western blot: 1:500-1:1000

technique(s)

immunofluorescence: suitable, immunohistochemistry: suitable, western blot: suitable

Immunogen

Synthetic peptide directed towards the N terminal region of human ACVR1C

Biochem/physiol Actions

ACVR1C is a type I receptor for the TGFB family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors.ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM].

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Other Notes

Synthetic peptide located within the following region: QVFCHSSNNVTKTECCFTDFCNNITLHLPTASPNAPKLGPMELAIIITVP

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Pricing

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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    Certificates of Analysis (COA)

    Lot/Batch Number
    QC25484

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