SAB2108690
Anti-MNX1
affinity isolated antibody
Synonym(s):
Anti- HLXB9, Anti- HOXHB9, Anti- SCRA1, Anti-HB9
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
40 kDa
species reactivity
human
concentration
0.5-1 mg/mL
technique(s)
immunoblotting: suitable
accession no.
NM_005515
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... MNX1(3110)
General description
Motor neuron and pancreas homeobox 1 (MNX1) gene is located on human chromosome 7q36.3. MNX1 contains a homeodomain, which encodes transcriptional factors for both solid and hematological malignancies.
Immunogen
Synthetic peptide directed towards the N terminal region of human MNX1
Application
Anti-MNX1 produced in rabbit has been used in immunohistochemistry and western blotting.
Biochem/physiol Actions
Motor neuron and pancreas homeobox 1 (MNX1) is known to cause permanent neonatal diabetes mellitus (PNDM), which is a rare monogenic disease. In bladder cancer, MNX1 is upregulated.
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Other Notes
Synthetic peptide located within the following region: AAASGTGGGGGGGGASGGTSGSCSPASSEPPAAPADRLRAESPSPPRLLA
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Transcription factor gene MNX1 is a novel cause of permanent neonatal diabetes in a consanguineous family
Bonnefond, et al.
Diabetes and Metabolism, 39(3), 276-280 (2013)
Currarino syndrome and HPE microform associated with a 2.7-Mb deletion in 7q36. 3 excluding SHH gene
Coutton,, et al.
Molecular Syndromology, 5(1), 25-31 (2014)
The dual role of HLXB9 in leukemia
Ferguson,, et al.
Pediatric Blood & Cancer, 56(3), 349-352 (2011)
Motor neuron and pancreas homeobox 1/HLXB9 promotes sustained proliferation in bladder cancer by upregulating CCNE1/2
Chen, Min, et al.
Journal of Experimental & Clinical Cancer Research, 37(1), 154-154 (2018)
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