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Merck
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SAB2500068

Anti-Androgen Receptor antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-AIS, Anti-AR, Anti-Dihydrotestosterone receptor, Anti-KD, Anti-TFM

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD01321686
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ChIP, ELISA (i), IHC, WB
Citations:
3

Key Documents

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biological source

goat

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

ChIP: suitable, immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable

UniProt accession no.

P10275

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... AR(367)

Related Categories

General description

Androgen receptor (AR) is a nuclear transcription factor. It belongs to the steroid hormone receptor superfamily. AR gene is located on human chromosome Xq12. AR is present in endothelial and vascular smooth muscle cells.

Immunogen

Peptide with sequence EVQLGLGRVYPRPPSC from the N Terminus of the protein sequence according to NP_000035.2.

Biochem/physiol Actions

Androgens like testosterone and 5α-dihydrotestosterone are required for the progression, growth, differentiation and maintenance of organ structure of the prostate. It plays a major role in normal and malignant breast tissue.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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pictograms

Exclamation mark
GHS07

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Warning

hcodes

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
6441P1

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FISH analysis of gene aberrations (MYC, CCND1, ERBB2, RB, and AR) in advanced prostatic carcinomas before and after androgen deprivation therapy.
Kaltz-Wittmer C, et al.
Laboratory Investigation; a Journal of Technical Methods and Pathology, 80(9), 1455?1464-1455?1464 (2000)
The CAG repeat polymorphism in the AR gene affects high density lipoprotein cholesterol and arterial vasoreactivity.
Zitzmann M, et al.
The Journal of Clinical Endocrinology and Metabolism, 86(10), 4867-4873 (2001)
Androgen receptor expression on circulating tumor cells in metastatic breast cancer.
Fujii T, et al.
PLoS ONE, 12(9), e0185231-e0185231 (2016)

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