SAB2500606
Anti-LXR α/LXR β antibody produced in goat
affinity isolated antibody, buffered aqueous solution
Synonym(s):
Anti-NR1H3, Anti-RLD-1
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), WB
Species reactivity:
human
Citations:
2
Technique(s):
indirect ELISA: suitable, western blot: suitable
Uniprot accession no.:
biological source
goat
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
indirect ELISA: suitable, western blot: suitable
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... NR1H3; NR1H2(10062)
Biochem/physiol Actions
Liver X receptor α (LXR-α) has an important role in the control of cholesterol homeostasis. LXRs have been found to regulate inflammatory response in macrophages. They are also involved in the regulation of cell proliferation.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
General description
Liver X receptor α and β (LXR-α/LXR-β) are members of LXRs that belong to the nuclear receptor superfamily. LXR-α is expressed predominantly in macrophages, liver, intestine, kidney, lung and adipose tissue. The protein contains a DNA-binding domain that requires the ligand-binding domain to heterodimerize with a retinoid X receptor partner for its DNA-binding activity. The gene encoding this protein is localized on to human chromosome 11p11.2.
Immunogen
Peptide with sequence CRLQDKKLPPLLSEI from the internal region of the protein sequence according to NP_005684; NP_009052.
Physical form
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
Not finding the right product?
Try our Product Selector Tool.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
CCAR2 negatively regulates nuclear receptor LXRa by competing with SIRT1 deacetylase.
Sakurabashi A
The Journal of Steroid Biochemistry and Molecular Biology (2015)
Liver x receptors in atherosclerosis and inflammation.
Im SS and Osborne TF
Circulation Research (2011)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service