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Merck
CN

SAB2501044

Anti-TIRAP/MAL (Isoform B) antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-Adapter protein wyatt, Anti-Mal, Anti-Toll-interleukin 1 receptor (TIR) domain-containing adapter protein

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD03456039
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), WB
Citations:
2

Key Documents

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biological source

goat

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

indirect ELISA: suitable, western blot: suitable

UniProt accession no.

P58753

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... TIRAP(114609)

Related Categories

General description

TIR domain containing adaptor protein (TIRAP) is an adaptor protein and the gene encoding it is localized on human chromosome 11q24.2.

Immunogen

Peptide with sequence C-EGEGERDSATVSDL from the C Terminus of the protein sequence according to NP_683708.1.

Biochem/physiol Actions

TIR domain containing adaptor protein (TIRAP) takes part in the toll-like receptor 4 (TLR4) signaling pathway. It activates various proteins and indirectly influences the release of inflammatory cytokines. This protein also has a role in the activation of proinflammatory genes.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
5187S2P2
5187S2

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Find documentation for the products that you have recently purchased in the Document Library.

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Role of S180L polymorphism in etiology of malaria caused by Plasmodium falciparum in a small group of Pakistani population.
Nawaz SK
Bosnian Journal of Basic Medical Sciences / Udruzenje Basicnih Mediciniskih Znanosti = Association of Basic Medical Sciences (2015)
Genetic variants in the TIRAP gene are associated with increased risk of sepsis-associated acute lung injury.
Song Z
BMC Medical Genetics (2010)

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