Anti-MYO5A antibody produced in goat

Myosin VA gene is mapped to human chromosome 15q21.2. It is a two-headed actin-based processive motor protein. Myosin VA comprises two heavy chains. Each chain has N-terminal motor domain, a neck region with six light chains and a coiled-coil and globular domain comprising tail region.

Peptide with sequence ETKQLELDLN, from the internal region of the protein sequence according to NP_000250.3; NP_001135967.1

Myosin VA associates with the microtubule-based motors and mediates organelle transport. It associates with Ras-related protein Rab-10 and mediates the glucose transporter type 4 translocation to plasma membrane. Mutations in the myosin VA is implicated in hypopigmentation disorder, Griscelli syndrome (GS1) and Elejalde syndrome.

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Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.

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