Skip to Content
Merck
CN

SAB2501686

Anti-NOX1 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(s):

GP91-2, MOX1, NADPH oxidase 1, NOH-1

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

NACRES:
NA.41
UNSPSC Code:
12352203

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Anti-NOX1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution

biological source

goat

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

mouse, human, bovine, canine

technique(s)

indirect ELISA: suitable
western blot: suitable

UniProt accession no.

Q9Y5S8

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... NOX1(27035)

Related Categories

Application

Anti-NOX1 antibody produced in goat has been used for Western blotting.

Biochem/physiol Actions

NOX1 catalyzes the production of hydrogen peroxide (H2O2). Overexpression of the protein leads to the production of superoxide and H2O2 and triggers angiogenic switch, mediating vascularization and rapid expansion of the tumor. Elevated expression of NOX1 has been observed in the brain of Parkinson′s disease (PD) patients.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

General description

NADPH oxidase 1 (NOX1) is encoded by the gene mapped to human chromosome Xq22.1. The protein belongs to the family of NADPH oxidases and is co-localized with caveolin in punctate patches on the surface and laterally on the cellular margins. NOX1 is mainly expressed in colon epithelium.

Immunogen

Peptide with sequence C-DKATDIVTGLKQK, from the internal region of the protein sequence according toNP_008983.2; NP_39249.1

Physical form

Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.

Not finding the right product?  

Try our Product Selector Tool.

Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

新产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0578C2
0578P1
10578P1

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

LRRC8A channels support TNFa-induced superoxide production by Nox1 which is required for receptor endocytosis
Hyehun Choi
Free Radical Biology & Medicine, 413-423 (2016)
Reactive oxygen generated by Nox1 triggers the angiogenic switch
Jack L
Proceedings of the National Academy of Sciences of the USA, 99(2), 715-720 (2000)
Distinct Subcellular Localizations of Nox1 and Nox4 in Vascular Smooth Muscle Cells
Lula L
Arteriosclerosis, Thrombosis, and Vascular Biology, 24(4) (2004)
NADPH oxidases in Parkinson?s disease: a systematic review
Karim Belarbi
Molecular Neurobiology, 12(84) (2017)
Nox1 NADPH oxidase is necessary for late but not early myocardial ischaemic preconditioning
Shuxia Jiang
Cardiovascular Research, 102(1) (2014)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service