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Merck
CN

SAB2702152

Monoclonal Anti-COPS5 antibody produced in mouse

Synonym(s):

CSN5, JAB1, MOV-34, SGN5

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203

Key Documents

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biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

2A10
monoclonal

form

liquid

mol wt

38 kDa

species reactivity

human, rat, mouse, Drosophila

concentration

1 mg/mL

technique(s)

immunocytochemistry: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: 1:500-1:3000

isotype

IgG2b

UniProt accession no.

Q92905

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... COPS5(10987)

Related Categories

Application

For IP: Use at a concentration of 0.5 - 1 μg/mL. For WB: Use at a dilution of 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher.

Biochem/physiol Actions

JAB-1 is a 38 kDa protein which was originally described as a coactivator for cJUN. It is present in a large protein complex called the ""Signalosome"", which has been proposed to play a signaling role in mammalian cells. This protein complex appears to be analogous to the COP9 complex in plants, which is important in light-mediated plant development. Although the specific function of JAB-1 in this complex is unclear, it has recently been implicated in targeting proteins for degradation by the proteasome.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Immunogen

The full-length mouse JAB-1 gene expressed in E. coli.

Physical form

Phosphate-buffered saline, pH 7.4, containing no preservatives

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Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品
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Certificates of Analysis (COA)

Lot/Batch Number
GT29247-03

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