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Merck
CN

SAB3500350

Anti-β-Actin (ACTB) Antibody

chicken polyclonal

Synonym(s):

Anti-β-actin

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD00164531
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), WB
Citations:
32

Key Documents

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Product Name

Anti-β-Actin antibody produced in chicken, affinity isolated antibody, buffered aqueous solution

biological source

chicken

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

rat, human, mouse

technique(s)

indirect ELISA: suitable, western blot: suitable

NCBI accession no.

AAH02409

UniProt accession no.

P60709

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... ACTB(60)

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General description

The amino-terminal of actin may function as an antigen. The protein is expressed in the cytoplasm. There are about six isoforms of actin identified.

Immunogen

β-actin antibody was raised against a 16 amino acid peptide from near the carboxy-terminus of human β-actin.

Application

Anti-β-Actin antibody produced in chicken has been used for Western Blotting.

Biochem/physiol Actions

Actin is a cytoskeletal protein that regulates cell motility, secretion, cytoplasmic streaming, phagocytosis and cytokinesis. Mutations in the gene encoding this protein have been associated with Baraitser-Winter cerebrofrontofacial syndrome.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied in PBS with 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品
低风险生物材料
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Certificates of Analysis (COA)

Lot/Batch Number
50050902

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Rachel E Bennett et al.
Proceedings of the National Academy of Sciences of the United States of America, 115(6), E1289-E1298 (2018-01-24)
Mixed pathology, with both Alzheimer's disease and vascular abnormalities, is the most common cause of clinical dementia in the elderly. While usually thought to be concurrent diseases, the fact that changes in cerebral blood flow are a prominent early and
Regulation of the macrophage oxytocin receptor in response to inflammation
Angela Szeto
The American Journal of Physiology (2017)
?-Actin specifically controls cell growth, migration, and the G-actin pool
Tina M Bunnell
Molecular Biology of the Cell, 22 (2011)
Ling Fu et al.
Oncology letters, 15(4), 5081-5086 (2018-03-20)
Sorafenib is a multikinase inhibitor that is frequently used to treat various types of malignant tumors. However, it has been demonstrated that Sorafenib only has a moderate antitumor efficacy and is associated with numerous side effects in non-small cell lung
Angela Szeto et al.
Lipids in health and disease, 19(1), 188-188 (2020-08-21)
Obesity and adipose tissue expansion is characterized by a chronic state of systemic inflammation that contributes to disease. The neuropeptide, oxytocin, working through its receptor has been shown to attenuate inflammation in sepsis, wound healing, and cardiovascular disease. The current
View All Related Papers

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