SAB3501078
Anti-TMIGD1 antibody produced in rabbit
affinity isolated antibody
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Product Name
Anti-TMIGD1 antibody produced in rabbit, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
predicted mol wt 29 kDa
species reactivity
rat, mouse, human
concentration
1 mg/mL
technique(s)
ELISA: suitable
immunoblotting: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... TMIGD1(388364)
Application
Anti-TMIGD1 antibody produced in rabbit is suitable for immunoblot and ELISA.
Biochem/physiol Actions
TMIGD1 (Transmembrane and immunoglobulin domain containing 1) is involved in various cellular processes such as regulation of cell structure, cell-cell adhesion, and cellular movement. Its extracellular domain stabilizes the cell morphology and cell-cell interaction. TMIGD1 plays an important role in cell survival by protecting it from oxidative cell injury. It protects cells from oxidative and nutrient-deprivation-induced cell injury by stabilizing the transepithelial electric resistance and permeability of renal epithelial cells.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
General description
TMIGD1 (Transmembrane and immunoglobulin domain containing 1) is a novel adhesion molecule expressed in several organs and tissues, specifically in renal tubular epithelial cells. It is composed of two putative immunoglobulin domains, which mediates self-dimerization.
Immunogen
Antibody was raised against an 18 amino acid peptide near the center of human TMIGD1.
Other Notes
The action of this antibody can be blocked using blocking peptide SBP3501078.
Physical form
Supplied at 1 mg/mL in PBS with 0.02% sodim azide.
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Storage Class
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Emad Arafa et al.
The American journal of pathology, 185(10), 2757-2767 (2015-09-08)
Oxidative damage to renal tubular epithelial cells is a fundamental pathogenic mechanism implicated in both acute kidney injury and chronic kidney diseases. Because epithelial cell survival influences the outcome of acute kidney injury and chronic kidney diseases, identifying its molecular
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