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SAB4200718

Anti-Elastin antibody, Mouse monoclonal

Name: Anti-Elastin antibody, Mouse monoclonal
Brand: SIGMA

clone BA-4, purified from hybridoma cell culture

Synonym(s):

Anti-ELN, Anti-Tropoelastin

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About This Item

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

BA-4, monoclonal

Application:

IHC, IP

Citations:

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biological source

mouse

Quality Level

200

conjugate

unconjugated

antibody form

purified from hybridoma cell culture

antibody product type

primary antibodies

clone

BA-4, monoclonal

form

buffered aqueous solution

species reactivity

sheep, hamster, bovine, goat, frog, rabbit, porcine, human, guinea pig, canine

concentration

~1.0 mg/mL

technique(s)

immunoblotting: suitable, immunohistochemistry: 10-20 μg/mL using enzyme-retrieved formalin-fixed, paraffin-embedded sheep arterial tissue sections, immunoprecipitation (IP): suitable

isotype

IgG1

UniProt accession no.

P15502

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... EMILIN3(2006)

General description

Anti-Elastin antibody, Mouse monoclonal (mouse IgG1 isotype) is derived from the BA-4 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from a BALB/c mouse immunized with bovine alpha-Elastin.

Immunogen

bovine alpha-Elastin

Application

Anti-Elastin antibody, Mouse monoclonal has been used in:

immunohistochemistry
immunoblot
immunoprecipitation

Biochem/physiol Actions

Elastin (ELN) provides elasticity and is integrated with other proteins from the ECM in elastic fibrils. Elastin undergoes changes of morphology with aging and at many disease states. In addition, several heritable diseases, such as supravalvular aortic stenosis, cutis laxa, Marfan syndrome, pseudoxanthoma elasticum and Buschke-Ollendorf syndrome, may result from molecular defects of elastin.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

低风险生物材料

常规特殊物品

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Certificates of Analysis (COA)

Lot/Batch Number

0000512413

0000358464

0000339691

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Elastin

Biochemistry of Collagens, Laminins and Elastin, 197-201 (2016)

Impaired elastogenesis in Hurler disease: dermatan sulfate accumulation linked to deficiency in elastin-binding protein and elastic fiber assembly

Hinek A and Wilson SE

The American Journal of Pathology, 156(3), 925-938 (2000)

Elastogenesis in human arterial disease: a role for macrophages in disordered elastin synthesis.

Krettek A, et al.

Arteriosclerosis, Thrombosis, and Vascular Biology, 23(4), 582-587 (2003)

Global Trade Item Number

SKU	GTIN
SAB4200718-100UL	04061837884429

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