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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
BA-4, monoclonal
Application:
IHC, IP
Citations:
3
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified from hybridoma cell culture
antibody product type
primary antibodies
clone
BA-4, monoclonal
form
buffered aqueous solution
species reactivity
sheep, hamster, bovine, goat, frog, rabbit, porcine, human, guinea pig, canine
concentration
~1.0 mg/mL
technique(s)
immunoblotting: suitable, immunohistochemistry: 10-20 μg/mL using enzyme-retrieved formalin-fixed, paraffin-embedded sheep arterial tissue sections, immunoprecipitation (IP): suitable
isotype
IgG1
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... EMILIN3(2006)
General description
Anti-Elastin antibody, Mouse monoclonal (mouse IgG1 isotype) is derived from the BA-4 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from a BALB/c mouse immunized with bovine alpha-Elastin.
Immunogen
bovine alpha-Elastin
Application
Anti-Elastin antibody, Mouse monoclonal has been used in:
- immunohistochemistry
- immunoblot
- immunoprecipitation
Biochem/physiol Actions
Elastin (ELN) provides elasticity and is integrated with other proteins from the ECM in elastic fibrils. Elastin undergoes changes of morphology with aging and at many disease states. In addition, several heritable diseases, such as supravalvular aortic stenosis, cutis laxa, Marfan syndrome, pseudoxanthoma elasticum and Buschke-Ollendorf syndrome, may result from molecular defects of elastin.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
常规特殊物品
低风险生物材料
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Related Content
Elastin
Biochemistry of Collagens, Laminins and Elastin, 197-201 (2016)
Impaired elastogenesis in Hurler disease: dermatan sulfate accumulation linked to deficiency in elastin-binding protein and elastic fiber assembly
Hinek A and Wilson SE
The American Journal of Pathology, 156(3), 925-938 (2000)
Elastogenesis in human arterial disease: a role for macrophages in disordered elastin synthesis.
Krettek A, et al.
Arteriosclerosis, Thrombosis, and Vascular Biology, 23(4), 582-587 (2003)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SAB4200718-100UL | 04061837884429 |