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SAB4200734

Anti-IL6 high affinity antibody, Mouse monoclonal

Name: Anti-IL6 high affinity antibody, Mouse monoclonal
Brand: SIGMA

clone IL6-2A3, purified from hybridoma cell culture

Synonym(s):

Anti-B-cell stimulatory factor 2 (BSF-2), Anti-CTL differentiation factor (CDF), Anti-Hybridoma growth factor, Anti-Interferon beta-2 (IFN-beta-2), Anti-Interleukin-6

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About This Item

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

IL6-2A3, monoclonal

Application:

ELISA, IP

Citations:

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Properties

Quality Segment

200

biological source

mouse

conjugate

unconjugated

antibody form

purified from hybridoma cell culture

antibody product type

primary antibodies

clone

IL6-2A3, monoclonal

form

buffered aqueous solution

species reactivity

human

concentration

~1.0 mg/mL

technique(s)

ELISA: suitable, immunoblotting: 0.125-0.25 μg/mL using recombinant human IL6 expressed in HEK-293T cells, immunoprecipitation (IP): 10-20 μg/test using concentrated supernatant of human osteosarcoma MG-63 cells treated with IL1β

isotype

IgG2a

UniProt accession no.

P05231

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... IL6(3569)

Description

General description

Interleukin-6 (IL6) is a multifunctional cytokine.

Immunogen

recombinant human IL6

Application

Anti-IL6 high affinity antibody, Mouse monoclonal has been used in

immunoblotting
immunoprecipitation
ELISA

Biochem/physiol Actions

Interleukin-6 (IL6) plays a wide variety of important biological roles in the immune, nervous and endocrine system. It is an essential component for hybridoma growth and is found in many supplemental cloning media. IL6 regulates acute and chronic inflammatory diseases and has been proven to be an excellent target for clinical treatment against autoimmune disorders such as rheumatoid arthritis, juvenile idiopathic arthritis and Castleman′s disease. IL6 also plays a key role in the pathogenesis of multiple myeloma.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

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Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c