SAB4200742
Anti-c-Myc-Peroxidase antibody, Mouse monoclonal
clone 9E10, purified from hybridoma cell culture
Synonym(s):
Anti-MRTL, Anti-Myc, Anti-bHLHe39, Anti-v-myc avian myelocytomatosis viral oncogene homolog
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About This Item
NACRES:
NA.56
UNSPSC Code:
12352203
Conjugate:
peroxidase conjugate
Clone:
9E10, monoclonal
Application:
immunoblotting
immunohistochemistry
immunohistochemistry
Species reactivity:
human
Citations:
6
Technique(s):
immunoblotting: 1:250-1:500 using lysate of HEK-293T cells over expressing c-Myc fusion protein
immunohistochemistry: suitable
immunohistochemistry: suitable
Uniprot accession no.:
Product Name
Anti-c-Myc-Peroxidase antibody, Mouse monoclonal, clone 9E10, purified from hybridoma cell culture
biological source
mouse
conjugate
peroxidase conjugate
antibody form
purified from hybridoma cell culture
antibody product type
primary antibodies
clone
9E10, monoclonal
form
lyophilized powder
species reactivity
human
packaging
vial of 100 μL
vial of 500 μL
concentration
~2 mg/mL
technique(s)
immunoblotting: 1:250-1:500 using lysate of HEK-293T cells over expressing c-Myc fusion protein
immunohistochemistry: suitable
isotype
IgG1
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... MYC(4609)
Application
Anti-c-Myc-Peroxidase antibody, Mouse monoclonal may be used in immunoblotting and immunohistology.
Biochem/physiol Actions
Monoclonal Anti-Calponin specifically recognizes smooth muscle Calponin.
c-Myc is a transcription factor involved in regulation of cell growth, proliferation, differentiation and apoptosis. It is implicated in DNA replication, RNA splicing or transcription. Increased expression of the gene is associated with the development of various types of human cancers.
Disclaimer
Unless otherwise stated in our catalog, our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Monoclonal Anti-c-Myc (mouse IgG1 isotype) is derived from the 9E10 hybridoma, produced by the fusion of mouse myeloma cells and splenocytes from a BALB/c mouse immunized with synthetic peptide of the human p62c-myc protein, conjugated to KLH. c-Myc is a proto-oncogene localized on long arm of human chromosome 8. The encoded protein contains an N-terminal transactivation domain. The human c-Myc proto-oncogene is the cellular homolog of the avian v-Myc gene found in several leukemogenic retroviruses.
Immunogen
Synthetic peptide of the human p62c-myc protein.
Physical form
Supplied as lyophilized powder. After reconstitution with 0.1 mL/0.5 ml of distilled water to a final antibody concentration of ∼ 2 mg/mL, the solution contains 1% BSA, 2.5% trehalose, 0.05% MIT in 0.01 M sodium phosphate buffered saline
Preparation Note
Store the lyophilized product at 2–8 °C. For extended storage after reconstitution, keep at –20 °C in working aliquots. Avoid repeated freeze-thaw cycles. For continuous use after reconstitution, keep at 2–8 °C for up to 1 month. Solutions at working dilution should be discarded if not used within 12 hours.
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signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
Storage Class
13 - Non Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Find documentation for the products that you have recently purchased in the Document Library.
The c-Myc target gene network
Dang CV, et al.
Seminars in Cancer Biology, 16(4), 253-264 (2006)
Prognostic Value of c-Myc Immunohistochemical Expression in Muscle Invasive Urothelial Carcinoma of the Urinary Bladder: A Retrospective Study
Elwy AE, et al.
Asian Pacific Journal of Cancer Prevention, 20(12), 3735-3735 (2019)
Lin Zhu et al.
eLife, 12 (2024-01-29)
Viral inclusion bodies (IBs) commonly form during the replication of Ebola virus (EBOV) in infected cells, but their role in viral immune evasion has rarely been explored. Here, we found that interferon regulatory factor 3 (IRF3), but not TANK-binding kinase
Hainan Liu et al.
Journal of virology, 96(12), e0041222-e0041222 (2022-06-03)
SARS-CoV-2 is the causative agent of the ongoing pandemic of coronavirus disease 2019 (COVID-19) and poses a significant threat to global health. N protein (NP), which is a major pathogenic protein among betacoronaviruses, binds to the viral RNA genome to
Tong Zheng et al.
Journal of virology, 98(4), e0156523-e0156523 (2024-03-06)
The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has posed a worldwide threat in the past 3 years. Although it has been widely and intensively investigated, the mechanism underlying the coronavirus-host interaction requires further elucidation, which
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