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SAB4300398

Anti-MAP3K5 (Ab-83) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-ASK1 antibody produced in rabbit, Anti-MAPKKK5 antibody produced in rabbit, Anti-MEKK5 antibody produced in rabbit, Anti-mitogen-activated protein kinase kinase kinase 5 antibody produced in rabbit

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD02262559
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IF, IHC (p), WB
Citations:
4
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biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~155 kDa

species reactivity

human

concentration

1 mg/mL

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100, indirect immunofluorescence: 1:100-1:200, western blot: 1:500-1:1000

isotype

IgG

immunogen sequence

(G-S-S-V-G)

NCBI accession no.

NP_005914.1

UniProt accession no.

Q99683

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MAP3K5(4217)

General description

Component of a protein kinase signal transduction cascade. Phosphorylates and activates MAP2K4 and MAP2K6, which in turn activate the JNK and p38 MAP kinases, respectively. Overexpression induces apoptotic cell death.

Immunogen

Peptide sequence around aa. 81-85 (G-S-S-V-G), according to the protein MAP3K5.

Features and Benefits

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Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

新产品

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Certificates of Analysis (COA)

Lot/Batch Number
871521125

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Philipp Grubwieser et al.
Frontiers in cellular and infection microbiology, 12, 875543-875543 (2022-06-07)
Pneumonia is often elicited by bacteria and can be associated with a severe clinical course, respiratory failure and the need for mechanical ventilation. In the alveolus, type-2-alveolar-epithelial-cells (AECII) contribute to innate immune functions. We hypothesized that AECII actively adapt cellular
Alexander Hoffmann et al.
EBioMedicine, 71, 103568-103568 (2021-09-07)
Iron deficiency anaemia (IDA) is a major health concern. However, preventive iron supplementation in regions with high burden of infectious diseases resulted in an increase of infection related morbidity and mortality. We fed male C57BL/6N mice with either an iron
Philipp Grubwieser et al.
Frontiers in microbiology, 14, 1223113-1223113 (2023-08-28)
Klebsiella pneumoniae (KP) is a major cause of hospital-acquired infections, such as pneumonia. Moreover, it is classified as a pathogen of concern due to sprawling anti-microbial resistance. During infection, the gram-negative pathogen is capable of establishing an intracellular niche in
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Global Trade Item Number

SKUGTIN
SAB4300398-100UG04061831497038