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SAB4300434

Anti-PAK1/PAK2/PAK3 (Ab-423/402/421) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-CDKN1A antibody produced in rabbit, Anti-MGC130000 antibody produced in rabbit, Anti-PAK65 antibody produced in rabbit, Anti-p21 protein (Cdc42 / Rac)-activated kinase 1 / 2 / 3 antibody produced in rabbit

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD02097133
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IF, IHC (p)
Citations:
-
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biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

61-67 kDa, 68-74 kDa

species reactivity

rat, human, mouse

concentration

1 mg/mL

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100, indirect immunofluorescence: 1:100-1:200

isotype

IgG

immunogen sequence

(R-S-T-M-V)

NCBI accession no.

NP_001121638.1, NP_001122092.1, NP_002568.2

UniProt accession no.

Q13177

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... PAK1(5058), PAK2(5062), PAK3(5063)

General description

The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.

Immunogen

Peptide sequence around aa. 421-425/400-404/419-423 (R-S-T-M-V), according to the proteins PAK1/PAK2/PAK3.

Features and Benefits

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Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

新产品

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Certificates of Analysis (COA)

Lot/Batch Number
871521169

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Global Trade Item Number

SKUGTIN
SAB4300434-100UG04061831497151