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Merck
CN

SAB4300596

Anti-CDK6 (Ab-24) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-MGC59692 antibody produced in rabbit, Anti-PLSTIRE antibody produced in rabbit, Anti-STQTL11 antibody produced in rabbit, Anti-cyclin-dependent kinase 6 antibody produced in rabbit

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203

Key Documents

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Product Name

Anti-CDK6 (Ab-24) antibody produced in rabbit, affinity isolated antibody

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~36 kDa

species reactivity

human, rat, mouse

concentration

1 mg/mL

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
western blot: 1:500-1:1000

isotype

IgG

immunogen sequence

(G-A-Y-G-K)

NCBI accession no.

NP_001138778.1

UniProt accession no.

Q00534

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... CDK6(1021)

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

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General description

Probably involved in the control of the cell cycle. Interacts with D-type G1 cyclins.

Immunogen

Peptide sequence around aa. 22-26 (G-A-Y-G-K), according to the protein CDK6.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
951421543

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Jiaqi Wang et al.
International journal of oncology, 60(2) (2022-01-05)
miR‑1291 exerts an anti‑tumor effect in a subset of human carcinomas, including pancreatic cancer. However, its role in colorectal cancer (CRC) is largely unknown. In the present study, the expression and effect of miR‑1291 in CRC cells was investigated. It
Rebecca E Nakles et al.
The American journal of pathology, 182(6), 1976-1985 (2013-05-15)
Peroxisome proliferator-activated receptor gamma (PPARγ) agonists have anticancer activity and influence cell differentiation. We examined the impact of the selective PPARγ agonist efatutazone on mammary cancer pathogenesis in a mouse model of BRCA1 mutation. Mice with conditional loss of full-length

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