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Merck
CN

SAB4300614

Anti-ARNTL antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-BMAL1 antibody produced in rabbit, Anti-BMAL1c antibody produced in rabbit, Anti-JAP3 antibody produced in rabbit, Anti-MGC47515 antibody produced in rabbit, Anti-aryl hydrocarbon receptor nuclear translocator-like antibody produced in rabbit

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About This Item

MDL number:
MFCD02262590
UNSPSC Code:
12352203
NACRES:
NA.41

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~69 kDa

species reactivity

rat, mouse, human

concentration

1 mg/mL

technique(s)

western blot: 1:500-1:1000

isotype

IgG

immunogen sequence

(S-S-S-I-L)

NCBI accession no.

NP_001025443.1

UniProt accession no.

O00327

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ARNTL(406)

General description

ARNTL-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription of a number of proteins of the circadian clock. This transcription is inhibited in a feedback loop by PER, and also by CRY proteins.

Immunogen

Peptide sequence around aa. 569-573 (S-S-S-I-L), according to the protein ARNTL.

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
951421415

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Brian A Hodge et al.
eLife, 8 (2019-02-23)
In the present study we show that the master myogenic regulatory factor, MYOD1, is a positive modulator of molecular clock amplitude and functions with the core clock factors for expression of clock-controlled genes in skeletal muscle. We demonstrate that MYOD1
Uduak S Udoh et al.
American journal of physiology. Gastrointestinal and liver physiology, 314(3), G431-G447 (2017-12-02)
Multiple metabolic pathways exhibit time-of-day-dependent rhythms that are controlled by the molecular circadian clock. We have shown that chronic alcohol is capable of altering the molecular clock and diurnal oscillations in several elements of hepatic glycogen metabolism ( 19
Brian A Hodge et al.
Skeletal muscle, 5, 17-17 (2015-05-23)
Skeletal muscle is a major contributor to whole-body metabolism as it serves as a depot for both glucose and amino acids, and is a highly metabolically active tissue. Within skeletal muscle exists an intrinsic molecular clock mechanism that regulates the

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