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Key Documents

SAB4301846

Sigma-Aldrich

Anti-CXCL6

affinity isolated antibody

Synonym(s):

CKA-3, GCP-2, SCYB6

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous glycerol solution

species reactivity

human

technique(s)

immunohistochemistry: 1: 100-300

accession no.

NP_002984

UniProt accession no.

P80162

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CXCL6(6372)

General description

CXCL6 (C-X-C motif chemokine ligand 6)/GCP-2 (granulocyte chemotactic protein-2), a pro-inflammatory neutrophil chemoattractant, is mapped to human chromosome 4q12-q13. It belongs to the ELR+ CXC family. It is synthesized by mesenchymal cells like fibroblasts and micro and macrovascular endothelial cells.

Immunogen

Synthetic peptide of human CXCL6

Biochem/physiol Actions

CXCL6 (C-X-C motif chemokine ligand 6)/GCP-2 (granulocyte chemotactic protein-2) plays an important role in the recruitment and activation of neutrophils. It acts as an autocrine growth factor resulting in tumor progression and metastasis. CXCL6 participates in menstruation, implantation and the maintenance of early pregnancy. GCP-2 plays an important role in mucosal chronic inflammatory conditions like inflammatory bowel disease or chronic rhinosinusitis.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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