biological source
rabbit
Quality Segment
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous glycerol solution
species reactivity
human
technique(s)
immunohistochemistry: 1: 100-300
accession no.
NP_002984
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... CXCL6(6372)
General description
CXCL6 (C-X-C motif chemokine ligand 6)/GCP-2 (granulocyte chemotactic protein-2), a pro-inflammatory neutrophil chemoattractant, is mapped to human chromosome 4q12-q13. It belongs to the ELR+ CXC family. It is synthesized by mesenchymal cells like fibroblasts and micro and macrovascular endothelial cells.
Immunogen
Synthetic peptide of human CXCL6
Biochem/physiol Actions
CXCL6 (C-X-C motif chemokine ligand 6)/GCP-2 (granulocyte chemotactic protein-2) plays an important role in the recruitment and activation of neutrophils. It acts as an autocrine growth factor resulting in tumor progression and metastasis. CXCL6 participates in menstruation, implantation and the maintenance of early pregnancy. GCP-2 plays an important role in mucosal chronic inflammatory conditions like inflammatory bowel disease or chronic rhinosinusitis.
Features and Benefits
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Physical form
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable